Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tbd_2425Probable transmembrane protein. (137 aa)    
Predicted Functional Partners:
hemF
Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
  
 0.950
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.948
Tbd_0635
Oxygen-independent coproporphyrinogen III oxidase HemN; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.922
Tbd_2424
N6-adenine-specific DNA methylase; Belongs to the methyltransferase superfamily.
       0.578
Tbd_2426
Hypothetical protein.
  
    0.576
Tbd_0840
Putative cytochrome c5.
  
     0.488
Tbd_1398
Putative cytochrome c-type protein.
  
     0.477
Tbd_0146
Probable cytochrome c5.
  
     0.444
hemE
Uroporphyrinogen decarboxylase HemE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
   
 0.418
Tbd_2368
Prepilin cysteine protease (C20) PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
   
    0.415
Your Current Organism:
Thiobacillus denitrificans ATCC 25259
NCBI taxonomy Id: 292415
Other names: T. denitrificans ATCC 25259, Thiobacillus denitrificans str. ATCC 25259, Thiobacillus denitrificans strain ATCC 25259
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