Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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ntrCTwo Component Transcriptional Regulator, Fis family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (476 aa)    
Predicted Functional Partners:
Tbd_2501
PAS/PAC Sensor Signal Transduction Histidine Kinase.
 0.996
Tbd_0533
Sigma-54 factor transcription regulator protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.773
Tbd_0732
RNA polymease sigma-54 factor protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.773
Tbd_2502
Conserved hypothetical protein.
       0.550
Tbd_1191
Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) and Response Regulator Receiver modulation.
  
 
 0.543
Tbd_1607
Flagellar motor switch protein FliM.
  
  
 0.523
Tbd_2468
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
     
 0.476
Tbd_1606
Probable flagellar transmembrane protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
  
 0.439
Tbd_1608
Flagellar motor switch/type III secretory pathway protein FliN.
  
  
 0.439
Tbd_0903
Multi-sensor Signal Transduction Histidine Kinase.
 
   0.438
Your Current Organism:
Thiobacillus denitrificans ATCC 25259
NCBI taxonomy Id: 292415
Other names: T. denitrificans ATCC 25259, Thiobacillus denitrificans str. ATCC 25259, Thiobacillus denitrificans strain ATCC 25259
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