STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tbd_2740Heavy metal translocating P-type ATPase. (689 aa)    
Predicted Functional Partners:
merA
Mercuric reductase MerA; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 
 0.827
merP
Mercuric transport protein periplasmic component; Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
 
 
 0.760
Tbd_1659
Probable copper ion binding protein.
 
 
 0.756
Tbd_2741
Conserved hypothetical protein.
 
     0.754
Tbd_2739
Transcription regulatory protein, ArsR family.
  
  
 0.695
Tbd_2736
Rhodanese-like protein.
  
  
 0.551
Tbd_2468
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
  
 0.533
Tbd_1324
Copper-resistance protein CopA.
 
  
 0.503
Tbd_2738
Putative metallo-beta-lactamase family protein.
  
    0.461
Tbd_2737
Conserved hypothetical protein.
       0.450
Your Current Organism:
Thiobacillus denitrificans ATCC 25259
NCBI taxonomy Id: 292415
Other names: T. denitrificans ATCC 25259, Thiobacillus denitrificans str. ATCC 25259, Thiobacillus denitrificans strain ATCC 25259
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.