STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STH115Pyruvate formate-lyase. (742 aa)    
Predicted Functional Partners:
STH114
Pyruvate formate lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
 0.998
STH838
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.952
STH3264
Pyruvate ferredoxin oxidoreductase gamma-delta subunit.
    
 0.943
STH3262
Pyruvate ferredoxin oxidoreductase alpha-beta subunit.
    
 0.938
STH2161
Branched-chain alpha-keto acid dehydrogenase E1 beta subunit.
   
 
 0.936
STH412
Pyruvate dehydrogenase E1 beta subunit.
   
 
 0.936
STH2162
Branched-chain alpha-keto acid dehydrogenase E1 alpha subunit.
   
 
 0.926
pdhA
Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 
 0.926
STH583
Branched-chain alpha-keto acid dehydrogenase E1 alpha subunit.
   
 
 0.926
STH1319
Malate oxidoreductase.
   
 
 0.925
Your Current Organism:
Symbiobacterium thermophilum
NCBI taxonomy Id: 292459
Other names: S. thermophilum IAM 14863, Symbiobacterium thermophilum IAM 14863, Symbiobacterium thermophilum str. IAM 14863, Symbiobacterium thermophilum strain IAM 14863
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