node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
STH1317 | STH3167 | STH1317 | STH3167 | 2-oxoacid:ferredoxin oxidoreductase alpha subunit. | Pyruvate flavodoxin dehydrogenase. | 0.999 |
STH1317 | aroC | STH1317 | STH1950 | 2-oxoacid:ferredoxin oxidoreductase alpha subunit. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.898 |
STH1408 | STH3129 | STH1408 | STH3129 | Anthranilate synthetase component II. | Phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.959 |
STH1408 | STH580 | STH1408 | STH580 | Anthranilate synthetase component II. | Putative anthranilate synthase component I. | 0.999 |
STH1408 | aroA | STH1408 | STH1419 | Anthranilate synthetase component II. | 3-phosphoshikimate-1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.509 |
STH1408 | aroB | STH1408 | STH1948 | Anthranilate synthetase component II. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.652 |
STH1408 | aroC | STH1408 | STH1950 | Anthranilate synthetase component II. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.944 |
STH1408 | aroE | STH1408 | STH1952 | Anthranilate synthetase component II. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.708 |
STH1408 | aroK | STH1408 | STH1949 | Anthranilate synthetase component II. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.466 |
STH1408 | trpE | STH1408 | STH1407 | Anthranilate synthetase component II. | Anthranilate synthetase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concen [...] | 0.999 |
STH3129 | STH1408 | STH3129 | STH1408 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Anthranilate synthetase component II. | 0.959 |
STH3129 | STH580 | STH3129 | STH580 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Putative anthranilate synthase component I. | 0.952 |
STH3129 | aroA | STH3129 | STH1419 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | 3-phosphoshikimate-1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.979 |
STH3129 | aroB | STH3129 | STH1948 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.970 |
STH3129 | aroC | STH3129 | STH1950 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.997 |
STH3129 | aroE | STH3129 | STH1952 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.890 |
STH3129 | aroK | STH3129 | STH1949 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.860 |
STH3129 | trpE | STH3129 | STH1407 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Anthranilate synthetase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concen [...] | 0.952 |
STH3167 | STH1317 | STH3167 | STH1317 | Pyruvate flavodoxin dehydrogenase. | 2-oxoacid:ferredoxin oxidoreductase alpha subunit. | 0.999 |
STH3167 | aroC | STH3167 | STH1950 | Pyruvate flavodoxin dehydrogenase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.934 |