Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
STH1968PTS system glucose-specific IIA component. (180 aa)    
Predicted Functional Partners:
STH2448
PTS system N-acetylglucosamine-specific enzyme IIABC component.
 0.999
STH350
PTS system N-acetylglucosamine-specific enzyme IIABC component.
 0.998
STH3279
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.991
STH955
PTS system phosphocarrier protein Hpr.
 
 0.958
STH3280
PTS system phosphocarrier protein Hpr.
  
 0.951
STH954
Beta-glucosidase; Belongs to the glycosyl hydrolase 1 family.
 
 0.948
STH2450
Alpha-galactosidase/6-phospho-beta-glucosidase.
 
  
 0.935
pgi
Glucose-6-phosphate isomerase.
    
 0.924
murQ
Putative sugar phosphate isomerase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.
    
 0.922
STH1280
N-acetylglucosamine-6-phosphate deacetylase.
    
 0.913
Your Current Organism:
Symbiobacterium thermophilum
NCBI taxonomy Id: 292459
Other names: S. thermophilum IAM 14863, Symbiobacterium thermophilum IAM 14863, Symbiobacterium thermophilum str. IAM 14863, Symbiobacterium thermophilum strain IAM 14863
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