Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STH2006Two-component sensor histidine kinase. (506 aa)    
Predicted Functional Partners:
STH2007
Two-component response regulator.
 
 0.968
STH2506
Two-component response regulator.
 
 0.917
STH3290
Two-component response regulator, CheY-like.
 
 0.907
STH731
Two-component response regulator.
 
 0.901
STH690
Two-component response regulator.
 
 0.866
STH1041
Two-component response regulator.
 
 0.857
STH3308
Two-component response regulator.
 
 0.857
STH415
Two-component response regulator.
 
 0.852
STH750
Two-component response regulator, probably involved in phosphate sensing.
 
 0.852
STH844
Two-component response regulator.
 
 0.849
Your Current Organism:
Symbiobacterium thermophilum
NCBI taxonomy Id: 292459
Other names: S. thermophilum IAM 14863, Symbiobacterium thermophilum IAM 14863, Symbiobacterium thermophilum str. IAM 14863, Symbiobacterium thermophilum strain IAM 14863
Server load: low (14%) [HD]