STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STH2182Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1148 aa)    
Predicted Functional Partners:
STH838
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.969
STH1189
acetyl-CoA carboxylase alpha subunit.
 
 0.959
STH3167
Pyruvate flavodoxin dehydrogenase.
    
 0.958
STH2542
Citrate synthase; Belongs to the citrate synthase family.
 
 0.956
STH586
Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
  
 
 0.954
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.950
STH1319
Malate oxidoreductase.
   
 0.946
STH2534
Malate dehydrogenase.
   
 0.946
STH1579
Putative propionyl-CoA carboxylase beta subunit.
 
 0.945
STH1317
2-oxoacid:ferredoxin oxidoreductase alpha subunit.
     
 0.935
Your Current Organism:
Symbiobacterium thermophilum
NCBI taxonomy Id: 292459
Other names: S. thermophilum IAM 14863, Symbiobacterium thermophilum IAM 14863, Symbiobacterium thermophilum str. IAM 14863, Symbiobacterium thermophilum strain IAM 14863
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.