STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STH2544Isocitrate dehydrogenase. (421 aa)    
Predicted Functional Partners:
STH3164
Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.989
STH2542
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.970
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
 
 
 0.968
STH1946
3-isopropylmalate dehydrogenase.
 
0.953
STH1317
2-oxoacid:ferredoxin oxidoreductase alpha subunit.
   
 
 0.936
STH1196
Glutamate/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.928
STH2805
Glutamate/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.928
STH230
Glutamate synthase large subunit.
    
 0.923
STH222
2-oxoglutarate oxidoreductase alpha subunit.
   
 
 0.916
STH1316
2-oxoacid:ferredoxin oxidoreductase beta subunit.
     
 0.913
Your Current Organism:
Symbiobacterium thermophilum
NCBI taxonomy Id: 292459
Other names: S. thermophilum IAM 14863, Symbiobacterium thermophilum IAM 14863, Symbiobacterium thermophilum str. IAM 14863, Symbiobacterium thermophilum strain IAM 14863
Server load: low (26%) [HD]