STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ46072.1Transcriptional regulator, LysR family; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: ModE molybdate transport repressor domain; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: mar:MAE_09380 transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Similar to Q4C186_CROWT Regulatory protein. (300 aa)    
Predicted Functional Partners:
AFZ46070.1
PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR000014:IPR003018:IPR003661:IPR 003594:IPR001789:IPR005467:IPR020606:IPR013656; KEGG: gvi:glr0718 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase [...]
  
  
 0.620
AFZ48730.1
KEGG: syp:SYNPCC7002_A0300 hypothetical protein; SPTR: Putative uncharacterized protein.
  
   
 0.552
AFZ48743.1
KEGG: cyt:cce_4144 hypothetical protein; SPTR: Putative uncharacterized protein.
  
   
 0.495
AFZ46585.1
Glutamate synthase (NADH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583:IPR006982:IPR002932:IPR002489:IPR 017932; KEGG: cyc:PCC7424_3654 glutamate synthase (ferredoxin); PFAM: glutamine amidotransferase class-II; glutamate synthase; ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin).
  
  
 0.491
AFZ46889.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932:IPR000583:IPR006982:IPR002932:IPR 002489; KEGG: cyp:PCC8801_3730 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin).
  
  
 0.491
AFZ46071.1
KEGG: ava:Ava_4789 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.481
AFZ47014.1
Hypothetical protein; InterPro IPR017964; KEGG: cyt:cce_3625 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.471
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.453
AFZ46209.1
Carbonate dehydratase; PFAM: Ribulose bisphosphate carboxylase, small chain; Bacterial transferase hexapeptide (three repeats); COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR017156:IPR001451:IPR000894; KEGG: cyt:cce_4280 carbon dioxide concentrating mechanism protein; PFAM: ribulose bisphosphate carboxylase small chain; transferase hexapeptide repeat containing protein; PRIAM: Carbonate dehydratase; SPTR: Carbon dioxide concentrating mechanism protein.
  
   
 0.433
AFZ46264.1
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: AMP-dependent synthetase and ligase; SPTR: Beta-ketoacyl synthase.
  
  
 0.407
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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