STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ46127.1PFAM: N-6 DNA Methylase; HsdM N-terminal domain; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR002296:IPR002052:IPR003356; KEGG: mar:MAE_56940 type I restriction enzyme M protein; PFAM: N-6 DNA methylase; SPTR: N-6 DNA Methylase family. (503 aa)    
Predicted Functional Partners:
AFZ46131.1
PFAM: Type I restriction modification DNA specificity domain; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: mmw:Mmwyl1_3199 restriction modification system DNA specificity subunit; PFAM: restriction modification system DNA specificity domain; SPTR: Restriction modification system DNA specificity domain.
 
 0.995
AFZ46807.1
PFAM: Type I restriction modification DNA specificity domain; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: xbo:XBJ1_1412 putative restriction-modification system specificity determinant; PFAM: restriction modification system DNA specificity domain; SPTR: Putative restriction-modification system specificity determinant.
 
 0.995
AFZ46129.1
PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Domain of unknown function (DUF3559); Type III restriction enzyme, res subunit; COGs: COG4096 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterProIPR014001:IPR014021:IPR001650:IPR007409:IPR 006935; KEGG: mar:MAE_56990 type III restriction enzyme res subunit; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; helicase domain protein; PRIAM: Type I site-specific deoxyribonuclease; SMART: DEAD-like helicase; SPTR: Type III restriction enzym [...]
 
 
 0.953
AFZ47199.1
PFAM: Restriction endonuclease; COGs: COG1715 Restriction endonuclease; InterPro IPR007560; KEGG: sfu:Sfum_2534 restriction endonuclease; PFAM: restriction endonuclease; SPTR: Restriction endonuclease.
 
  
 0.631
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.583
AFZ46989.1
COGs: COG1112 Superfamily I DNA and RNA helicase and helicase subunits; KEGG: pna:Pnap_4258 superfamily I DNA/RNA helicase; SPTR: Putative uncharacterized protein.
  
  
 0.550
AFZ46126.1
Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase.
  
  
 0.517
AFZ46849.1
PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA); COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: cyc:PCC7424_0710 fibronectin-binding A domain protein; PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; SPTR: Putative uncharacterized protein.
  
    0.509
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.478
AFZ48537.1
TIGRFAM: TIGR02688 family protein; COGs: COG4930 ATP-dependent Lon-type protease; InterPro IPR014061; KEGG: tro:trd_A0108 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.457
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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