STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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Experiments
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[Homology]
Score
AFZ46173.1Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000014:IPR001610:IPR000160:IPR001633:IPR 000700:IPR000215:IPR013767; KEGG: cyc:PCC7424_4938 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain contain [...] (943 aa)    
Predicted Functional Partners:
AFZ47818.1
PAS/PAC sensor hybrid histidine kinase; PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR000644:IPR013655:IPR013767:IPR 003661:IPR003594:IPR001789:IPR001610:IPR005467:IPR000700:I PR004358; KEGG: hmo:HM1_1611 sensor histidine kinase, putative; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; CBS domain containing protein; PAS fold domain protein; histidi [...]
 
 0.978
AFZ46070.1
PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR000014:IPR003018:IPR003661:IPR 003594:IPR001789:IPR005467:IPR020606:IPR013656; KEGG: gvi:glr0718 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase [...]
 
 0.977
AFZ48032.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR013655:IPR003018:IPR003661:IPR 003594:IPR001789:IPR001610:IPR005467:IPR000700:IPR004358; KEGG: gfo:GFO_0848 two-component system sensor histidine kinase/response regulator hybrid; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; GAF domain protein; response regulator rec [...]
 
 0.976
AFZ47413.1
PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR001789:IPR004358:IPR013767:IPR016132:I PR005467:IPR000700; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CBS domain containing protein; PAS fold domain pro [...]
 
 
 0.970
AFZ46223.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; GGDEF domain; FHA domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000253:IPR000014:IPR000160:IPR001633:IPR 013767; KEGG: cyt:cce_2788 hypothetical protein; PFAM: EAL domain protein; Forkhead-associated protein; PAS fold domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; Forkhead-associated protein; PAS domain c [...]
 
 
0.954
AFZ46539.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); PFAM: EAL domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR013655:IPR013767:IPR000160:IPR001633:IPR 000014:IPR000700:IPR001610:IPR003018; KEGG: cyc:PCC7424_1286 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold domain protein; PAS fold-3 domain protein; SMART: EAL domain protein; GGDEF [...]
 
 
0.950
AFZ46364.1
Multi-sensor hybrid histidine kinase; PFAM: CBS domain; Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR013655:IPR013656:IPR 003661:IPR003594:IPR001789:IPR016132:IPR005467:IPR000014:I PR000700:IPR004358:IPR001610; KEGG: ava:Ava_4701 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CB [...]
  
 
0.919
AFZ46261.1
Methyl-accepting chemotaxis sensory transducer with GAF sensor; PFAM: HAMP domain; GAF domain; Yeast cortical protein KAR9; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR003018:IPR004089:IPR016132; KEGG: cyh:Cyan8802_2776 methyl-accepting chemotaxis sensory transducer with GAF sensor; PFAM: chemotaxis sensory transducer; GAF domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; GAF domain protein; histidine kinase HAMP region domain protein; SPTR: Methyl-a [...]
 
 
 0.880
AFZ46260.1
Methyl-accepting chemotaxis sensory transducer with GAF sensor; PFAM: HAMP domain; GAF domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR003018:IPR004089:IPR016132; KEGG: cyh:Cyan8802_2778 methyl-accepting chemotaxis sensory transducer with GAF sensor; PFAM: chemotaxis sensory transducer; GAF domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; GAF domain protein; histidine kinase HAMP region domain protein; SPTR: Tsr or; CheD.
 
 
 0.874
AFZ47725.1
Integral membrane sensor hybrid histidine kinase; PFAM: Cache domain; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR003660:IPR003661:IPR003594:IPR 001789:IPR005467; KEGG: cyn:Cyan7425_3552 cache sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SMART: ATP-binding region ATPase dom [...]
 
 0.863
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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