STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ46373.1HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase; COGs: COG0546 phosphatase; InterPro IPR005834:IPR005833:IPR006402:IPR006439; KEGG: cyh:Cyan8802_1857 HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain [...] (245 aa)    
Predicted Functional Partners:
AFZ48722.1
HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; COGs: COG0546 phosphatase; InterPro IPR005834:IPR006439; KEGG: cyh:Cyan8802_3209 haloacid dehalogenase domain protein hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Haloacid dehalogenase domain protein hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1.
  
  
 0.933
cbbL
Ribulose 1,5-bisphosphate carboxylase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.
     
 0.904
AFZ46102.1
PFAM: Ribulose bisphosphate carboxylase, small chain; COGs: COG4451 Ribulose bisphosphate carboxylase small subunit; InterPro IPR000894; KEGG: cyc:PCC7424_1365 ribulose-bisphosphate carboxylase; PFAM: ribulose bisphosphate carboxylase small chain; PRIAM: Ribulose-bisphosphate carboxylase; SPTR: Ribulose-bisphosphate carboxylase.
     
 0.902
AFZ46399.1
Protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: Cysteine-rich domain; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017:IPR017896:IPR012257:IPR017900; KEGG: mar:MAE_44310 glycolate oxidase Fe-S subunit; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Glycolate oxidase Fe-S subunit.
     
 0.900
AFZ46494.1
FAD linked oxidase domain protein; PFAM: FAD binding domain; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR016166; KEGG: cyh:Cyan8802_1981 FAD linked oxidase domain protein; PFAM: FAD linked oxidase domain protein; SPTR: FAD linked oxidase domain protein.
     
 0.900
AFZ48173.1
Glycolate oxidase, subunit GlcD; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113:IPR016166:IPR004490; KEGG: cyh:Cyan8802_0851 glycolate oxidase, subunit GlcD; PFAM: FAD linked oxidase domain protein; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Glycolate oxidase, subunit GlcD; TIGRFAM: glycolate oxidase, subunit GlcD.
     
 0.900
AFZ46374.1
D-alanyl-D-alaninecarboxypeptidase/D-alanyl-D-al anine-endopeptidase; PFAM: D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; COGs: COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); InterPro IPR000667; KEGG: cyh:Cyan8802_0413 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: Peptidase S13, D-Ala-D-Ala carboxypeptidase C; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-al [...]
       0.648
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
     
 0.533
AFZ48447.1
KEGG: cyc:PCC7424_4615 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.531
AFZ46264.1
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: AMP-dependent synthetase and ligase; SPTR: Beta-ketoacyl synthase.
  
  
 0.492
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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