STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ46612.1NAD(P) transhydrogenase, alpha subunit; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: NAD(P) transhydrogenase, alpha subunit; COGs: COG3288 NAD/NADP transhydrogenase alpha subunit; InterPro IPR008143:IPR007886:IPR007698:IPR004571; KEGG: syn:slr1239 NAD(P) transhydrogenase subunit alpha; PFAM: alanine dehydrogenase/PNT domain protein; SPTR: Pyridine nucleotide transhydrogenase alpha subunit; TIGRFAM: NAD(P) transhydrogenase, alpha subunit. (530 aa)    
Predicted Functional Partners:
AFZ46609.1
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
 0.999
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.916
nadK-2
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.916
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.915
AFZ46020.1
PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; InterPro IPR004820:IPR004821:IPR005248; KEGG: cyc:PCC7424_0292 nicotinic acid mononucleotide adenylyltransferase; PFAM: cytidylyltransferase; SPTR: Nicotinate (Nicotinamide) nucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; Belongs to the NadD family.
     
 0.907
AFZ46610.1
PFAM: Protein of unknown function DUF86; COGs: COG2361 conserved hypothetical protein; InterPro IPR008201; KEGG: mac:MA0101 hypothetical protein; PFAM: protein of unknown function DUF86; SPTR: Putative uncharacterized protein.
       0.773
AFZ46611.1
DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain; COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: cyt:cce_4349 hypothetical protein; PFAM: DNA polymerase beta domain protein region; SPTR: Putative uncharacterized protein.
       0.773
AFZ46613.1
PFAM: Protein of unknown function (DUF433); InterPro IPR007367; KEGG: syn:ssl8008 hypothetical protein; PFAM: protein of unknown function DUF433; SPTR: Similar to tr|Q6ZE84|Q6ZE84_SYNY3 Ssl8008 protein.
       0.509
AFZ46614.1
KEGG: mar:MAE_18190 hypothetical protein; SPTR: Similar to tr|Q1F577|Q1F577_9CHLR Hypothetical protein.
       0.509
rpoC2
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
   
    0.463
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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