STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ46630.1HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005834:IPR006402:IPR005833; KEGG: HAD-superfamily hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: CbbY family protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3. (261 aa)    
Predicted Functional Partners:
cbbL
Ribulose 1,5-bisphosphate carboxylase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.
 
     0.737
AFZ46102.1
PFAM: Ribulose bisphosphate carboxylase, small chain; COGs: COG4451 Ribulose bisphosphate carboxylase small subunit; InterPro IPR000894; KEGG: cyc:PCC7424_1365 ribulose-bisphosphate carboxylase; PFAM: ribulose bisphosphate carboxylase small chain; PRIAM: Ribulose-bisphosphate carboxylase; SPTR: Ribulose-bisphosphate carboxylase.
 
   
 0.730
tadA
tRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
 
      0.696
AFZ46089.1
Hypothetical protein; PFAM: Zeta toxin; COGs: COG2187 conserved hypothetical protein; KEGG: cyp:PCC8801_2808 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.636
AFZ46189.1
PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: cyt:cce_3731 LysR family transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Rubisco operon transcriptional regulator.
  
   
 0.574
AFZ46264.1
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: AMP-dependent synthetase and ligase; SPTR: Beta-ketoacyl synthase.
  
 
 0.476
AFZ46265.1
Beta-ketoacyl synthase; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, N-terminal domain; AMP-binding enzyme; Sulfotransferase domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR000639:IPR009081:IPR006162:IPR018201:IPR 000873:IPR006163:IPR014030:IPR014031:IPR014043:IPR013968:I PR000863:IPR000073; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; phosphopantetheine-binding; AMP-dependent synthetase and ligase; Acyl transferase; KR do [...]
  
 
 0.476
glyS
PFAM: Glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, beta subunit; COGs: COG0751 Glycyl-tRNA synthetase beta subunit; InterPro IPR006194:IPR002311:IPR008909:IPR015944; KEGG: cyh:Cyan8802_2388 glycyl-tRNA synthetase, beta subunit; PFAM: glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain protein; PRIAM: Glycine--tRNA ligase; SPTR: Glycyl-tRNA synthetase, beta subunit; TIGRFAM: glycyl-tRNA synthetase, beta subunit.
       0.476
AFZ48067.1
PFAM: Phosphoribulokinase / Uridine kinase family; COGs: COG0572 Uridine kinase; InterPro IPR006082; KEGG: cyh:Cyan8802_3980 phosphoribulokinase; PRIAM: Phosphoribulokinase; SPTR: Phosphoribulokinase.
  
   0.436
AFZ47913.1
PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484; KEGG: cyp:PCC8801_2638 carbohydrate kinase FGGY; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Carbohydrate kinase FGGY.
 
   
 0.417
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
Server load: low (12%) [HD]
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