STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Coexpression
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[Homology]
Score
AFZ46677.1Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: cyc:PCC7424_1853 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase. (612 aa)    
Predicted Functional Partners:
AFZ47493.1
PFAM: Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182:IPR018365; KEGG: ava:Ava_1521 cell cycle protein; PFAM: cell cycle protein; SPTR: Cell cycle protein; Belongs to the SEDS family.
 
 0.976
AFZ47557.1
Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001990:IPR001460:IPR017790; KEGG: cyc:PCC7424_2896 penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 2; TIGRFAM: penicillin-binding protein 2.
  
  
 
0.923
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
 
 0.872
AFZ48249.1
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
  
 
 0.872
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
 0.815
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
  
 0.807
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
 
 0.806
AFZ46814.1
PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; FHA domain; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR000253:IPR001264:IPR001460; KEGG: cyc:PCC7424_3011 FHA modulated glycosyl transferase/transpeptidase; PFAM: glycosyl transferase family 51; Forkhead-associated protein; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SMART: Forkhead-associated protein; SPTR: FHA modulated glycosyl transferase/transpeptidase.
 
 
 
 0.804
AFZ47601.1
Cyanophycin synthetase; PFAM: RimK-like ATP-grasp domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: cyanophycin synthetase; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterProIPR003135:IPR013221:IPR004101:IPR011761:IPR 011810; KEGG: cyc:PCC7424_0873 cyanophycin synthetase; PFAM: Mur ligase middle domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Cyanophycin synthetase; TIGRFAM: cyanophycin synthetase.
  
 
 0.794
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.769
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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