STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ46748.1Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: cyt:cce_0877 geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase superfamily; Belongs to the FPP/GGPP synthase family. (294 aa)    
Predicted Functional Partners:
AFZ46544.1
Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.960
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
 
 0.933
AFZ47819.1
PFAM: Squalene/phytoene synthase; COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR002060:IPR019845; KEGG: cyc:PCC7424_1158 squalene/phytoene synthase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Squalene/phytoene synthase.
  
 0.926
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 
 0.922
AFZ47928.1
Geranylgeranyl reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: geranylgeranyl reductase; geranylgeranyl reductase family; COGs: COG0644 Dehydrogenase (flavoprotein); InterProIPR010253:IPR011774:IPR011777:IPR002938:IPR 003042; KEGG: syp:SYNPCC7002_A2476 geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; SPTR: Geranylgeranyl reductase; TIGRFAM: geranylgeranyl reductase.
  
 0.914
AFZ48102.1
PFAM: Polyprenyl synthetase; TIGRFAM: solanesyl diphosphate synthase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092:IPR014120; KEGG: cyh:Cyan8802_0383 solanesyl diphosphate synthase; PFAM: Polyprenyl synthetase; SPTR: Solanesyl diphosphate synthase; TIGRFAM: solanesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
 
0.912
AFZ46747.1
Acid phosphatase/vanadium-dependent haloperoxidase related protein; PFAM: Divergent PAP2 family; COGs: COG1963 conserved hypothetical protein; InterPro IPR003832; KEGG: mar:MAE_14560 hypothetical protein; PFAM: acid phosphatase/vanadium-dependent haloperoxidase related; SPTR: Putative uncharacterized protein.
       0.781
rnj
RNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
  
    0.638
AFZ46264.1
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: AMP-dependent synthetase and ligase; SPTR: Beta-ketoacyl synthase.
  
 
 0.548
AFZ46265.1
Beta-ketoacyl synthase; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, N-terminal domain; AMP-binding enzyme; Sulfotransferase domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR000639:IPR009081:IPR006162:IPR018201:IPR 000873:IPR006163:IPR014030:IPR014031:IPR014043:IPR013968:I PR000863:IPR000073; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; phosphopantetheine-binding; AMP-dependent synthetase and ligase; Acyl transferase; KR do [...]
  
 
 0.548
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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