| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFZ46126.1 | AFZ46216.1 | Cyast_0143 | Cyast_0235 | Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase. | PFAM: Domain of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: cyh:Cyan8802_3565 protein of unknown function DUF39; PFAM: protein of unknown function DUF39; SPTR: Putative uncharacterized protein. | 0.802 |
| AFZ46126.1 | AFZ47141.1 | Cyast_0143 | Cyast_1174 | Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.888 |
| AFZ46126.1 | AFZ47630.1 | Cyast_0143 | Cyast_1669 | Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase. | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR001216:IPR005856:IPR005859; KEGG: cyc:PCC7424_1502 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.915 |
| AFZ46126.1 | AFZ48555.1 | Cyast_0143 | Cyast_2612 | Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase. | PFAM: NIL domain; InterPro IPR017896:IPR018449:IPR017900; KEGG: ana:all0569 hypothetical protein; PFAM: NIL domain; SPTR: All0569 protein. | 0.802 |
| AFZ46126.1 | ahcY | Cyast_0143 | Cyast_0799 | Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.856 |
| AFZ46216.1 | AFZ46126.1 | Cyast_0235 | Cyast_0143 | PFAM: Domain of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: cyh:Cyan8802_3565 protein of unknown function DUF39; PFAM: protein of unknown function DUF39; SPTR: Putative uncharacterized protein. | Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase. | 0.802 |
| AFZ46216.1 | AFZ47141.1 | Cyast_0235 | Cyast_1174 | PFAM: Domain of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: cyh:Cyan8802_3565 protein of unknown function DUF39; PFAM: protein of unknown function DUF39; SPTR: Putative uncharacterized protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.934 |
| AFZ46216.1 | AFZ47630.1 | Cyast_0235 | Cyast_1669 | PFAM: Domain of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: cyh:Cyan8802_3565 protein of unknown function DUF39; PFAM: protein of unknown function DUF39; SPTR: Putative uncharacterized protein. | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR001216:IPR005856:IPR005859; KEGG: cyc:PCC7424_1502 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.802 |
| AFZ46216.1 | AFZ48555.1 | Cyast_0235 | Cyast_2612 | PFAM: Domain of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: cyh:Cyan8802_3565 protein of unknown function DUF39; PFAM: protein of unknown function DUF39; SPTR: Putative uncharacterized protein. | PFAM: NIL domain; InterPro IPR017896:IPR018449:IPR017900; KEGG: ana:all0569 hypothetical protein; PFAM: NIL domain; SPTR: All0569 protein. | 0.978 |
| AFZ46216.1 | ahcY | Cyast_0235 | Cyast_0799 | PFAM: Domain of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: cyh:Cyan8802_3565 protein of unknown function DUF39; PFAM: protein of unknown function DUF39; SPTR: Putative uncharacterized protein. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.900 |
| AFZ46426.1 | ahcY | Cyast_0446 | Cyast_0799 | DNA-cytosine methyltransferase; PFAM: HpaII restriction endonuclease; C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm); COGs: COG0270 Site-specific DNA methylase; InterPro IPR001525:IPR019062:IPR018117; KEGG: tdn:Suden_1839 DNA (cytosine-5-)-methyltransferase., type II site-specific deoxyribonuclease; PFAM: Restriction endonuclease, type II, HpaII; C-5 cytosine-specific DNA methylase; SPTR: Cytosine-specific methyltransferase; TIGRFAM: DNA-cytosine methyltransferase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.900 |
| AFZ47141.1 | AFZ46126.1 | Cyast_1174 | Cyast_0143 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase. | 0.888 |
| AFZ47141.1 | AFZ46216.1 | Cyast_1174 | Cyast_0235 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Domain of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: cyh:Cyan8802_3565 protein of unknown function DUF39; PFAM: protein of unknown function DUF39; SPTR: Putative uncharacterized protein. | 0.934 |
| AFZ47141.1 | AFZ47630.1 | Cyast_1174 | Cyast_1669 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR001216:IPR005856:IPR005859; KEGG: cyc:PCC7424_1502 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.888 |
| AFZ47141.1 | AFZ48555.1 | Cyast_1174 | Cyast_2612 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: NIL domain; InterPro IPR017896:IPR018449:IPR017900; KEGG: ana:all0569 hypothetical protein; PFAM: NIL domain; SPTR: All0569 protein. | 0.919 |
| AFZ47141.1 | ahcY | Cyast_1174 | Cyast_0799 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.961 |
| AFZ47272.1 | ahcY | Cyast_1307 | Cyast_0799 | DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm); COGs: COG0270 Site-specific DNA methylase; InterPro IPR001525:IPR018117; KEGG: mat:MARTH_orf138 cytosine-specific methyltransferase, related to HhaI; PFAM: C-5 cytosine-specific DNA methylase; SPTR: Cytosine-specific methyltransferase; TIGRFAM: DNA-cytosine methyltransferase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.900 |
| AFZ47630.1 | AFZ46126.1 | Cyast_1669 | Cyast_0143 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR001216:IPR005856:IPR005859; KEGG: cyc:PCC7424_1502 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase. | 0.915 |
| AFZ47630.1 | AFZ46216.1 | Cyast_1669 | Cyast_0235 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR001216:IPR005856:IPR005859; KEGG: cyc:PCC7424_1502 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PFAM: Domain of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: cyh:Cyan8802_3565 protein of unknown function DUF39; PFAM: protein of unknown function DUF39; SPTR: Putative uncharacterized protein. | 0.802 |
| AFZ47630.1 | AFZ47141.1 | Cyast_1669 | Cyast_1174 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR001216:IPR005856:IPR005859; KEGG: cyc:PCC7424_1502 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.888 |