STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ46972.1Carotenoid oxygenase; PFAM: Retinal pigment epithelial membrane protein; COGs: COG3670 Lignostilbene-alpha beta-dioxygenase; InterPro IPR004294; KEGG: cyc:PCC7424_0449 carotenoid oxygenase; PFAM: Carotenoid oxygenase; SPTR: Beta-carotene 15,15'-monooxygenase. (493 aa)    
Predicted Functional Partners:
AFZ47684.1
Phospholipase D/Transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: cyh:Cyan8802_3228 helix-hairpin-helix motif protein; PFAM: phospholipase D/Transphosphatidylase; SMART: phospholipase D/Transphosphatidylase; SPTR: Helix-hairpin-helix motif protein.
  
  
  0.607
AFZ46265.1
Beta-ketoacyl synthase; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, N-terminal domain; AMP-binding enzyme; Sulfotransferase domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR000639:IPR009081:IPR006162:IPR018201:IPR 000873:IPR006163:IPR014030:IPR014031:IPR014043:IPR013968:I PR000863:IPR000073; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; phosphopantetheine-binding; AMP-dependent synthetase and ligase; Acyl transferase; KR do [...]
  
 
 0.578
AFZ46879.1
Methyltransferase; PFAM: Uncharacterized conserved protein (DUF2260); TIGRFAM: probable methyltransferase; COGs: COG4301 conserved hypothetical protein; InterPro IPR019257:IPR017804; KEGG: methyltransferase; PFAM: Protein of unknown function DUF2260; SPTR: Putative uncharacterized protein; TIGRFAM: methyltransferase.
  
   
 0.566
AFZ46264.1
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: AMP-dependent synthetase and ligase; SPTR: Beta-ketoacyl synthase.
  
 
 0.517
AFZ47748.1
PFAM: Cytochrome P450; COGs: COG2124 Cytochrome P450; InterPro IPR002401:IPR017973:IPR001128:IPR017972; KEGG: cyh:Cyan8802_1139 cytochrome P450; PFAM: cytochrome P450; SPTR: Cytochrome P450.
  
   
 0.512
AFZ46973.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
       0.485
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
  
  
 0.481
AFZ47820.1
Zeta-carotene desaturase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: phytoene desaturase; COGs: COG3349 conserved hypothetical protein; InterPro IPR014102:IPR002937:IPR001613; KEGG: amr:AM1_4826 phytoene desaturase/phytoene desaturase; PFAM: amine oxidase; PRIAM: Carotene 7,8-desaturase; SPTR: Phytoene desaturase/phytoene desaturase; TIGRFAM: phytoene desaturase; three-step phytoene desaturase.
  
   
 0.429
AFZ46762.1
PFAM: Fatty acid desaturase; COGs: COG3239 Fatty acid desaturase; InterPro IPR005804; KEGG: cyc:PCC7424_2363 fatty acid desaturase; PFAM: fatty acid desaturase; SPTR: Fatty acid desaturase.
  
   
 0.409
AFZ48529.1
PFAM: Cytochrome P450; COGs: COG2124 Cytochrome P450; InterPro IPR001128:IPR017972:IPR002401:IPR017973; KEGG: cyt:cce_3728 cytochrome P450; PFAM: cytochrome P450; SPTR: Cytochrome P450.
  
   
 0.408
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
Server load: medium (46%) [HD]