STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (330 aa)    
Predicted Functional Partners:
cas2
CRISPR-associated protein, Cas2 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.994
cas2-2
CRISPR-associated protein, Cas2 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.973
AFZ47047.1
KEGG: syn:sll7069 hypothetical protein; SPTR: Sll7069 protein.
       0.795
cas1-2
CRISPR-associated exonuclease, Cas4 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 
0.785
AFZ48716.1
CRISPR-associated helicase, Cas3 family; PFAM: HD domain; Type III restriction enzyme, res subunit; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD; COGs: COG1203 helicase; InterProIPR001650:IPR014021:IPR014001:IPR006483:IPR 006474; KEGG: aco:Amico_0127 CRISPR-associated helicase Cas3; PFAM: helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: CRISPR-associated helicase Cas3; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated HD domain protein.
 
  
 0.742
AFZ47048.1
KEGG: syn:sll7070 hypothetical protein; SPTR: Putative uncharacterized protein sll7070.
       0.741
AFZ48715.1
PFAM: Cas6 Crispr; TIGRFAM: CRISPR-associated protein Cas6, subtype MYXAN; InterPro IPR014174; KEGG: lic:LIC10939 hypothetical protein; PFAM: CRISPR-associated protein Cas6-related; SPTR: Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein, Cas6-related.
 
  
 0.482
AFZ47049.1
Hypothetical protein; KEGG: pyo:PY03052 sporozoite surface protein 2 precursor; SPTR: Sporozoite surface protein 2.
       0.423
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.