| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFZ47235.1 | AFZ47236.1 | Cyast_1270 | Cyast_1271 | PFAM: Sodium:solute symporter family; COGs: COG0591 Na+/proline symporter; InterPro IPR001734:IPR018212; KEGG: amr:AM1_1166 Na+/proline symporter PutP, putative; PFAM: Na+/solute symporter; SPTR: Na+/proline symporter PutP, putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | 0.496 |
| AFZ47235.1 | AFZ47238.1 | Cyast_1270 | Cyast_1273 | PFAM: Sodium:solute symporter family; COGs: COG0591 Na+/proline symporter; InterPro IPR001734:IPR018212; KEGG: amr:AM1_1166 Na+/proline symporter PutP, putative; PFAM: Na+/solute symporter; SPTR: Na+/proline symporter PutP, putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR005924:IPR006035:IPR020855; KEGG: cyc:PCC7424_5245 agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; PRIAM: Agmatinase; SPTR: Arginase family; Belongs to the arginase family. | 0.537 |
| AFZ47235.1 | hypA | Cyast_1270 | Cyast_1272 | PFAM: Sodium:solute symporter family; COGs: COG0591 Na+/proline symporter; InterPro IPR001734:IPR018212; KEGG: amr:AM1_1166 Na+/proline symporter PutP, putative; PFAM: Na+/solute symporter; SPTR: Na+/proline symporter PutP, putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.549 |
| AFZ47236.1 | AFZ47235.1 | Cyast_1271 | Cyast_1270 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | PFAM: Sodium:solute symporter family; COGs: COG0591 Na+/proline symporter; InterPro IPR001734:IPR018212; KEGG: amr:AM1_1166 Na+/proline symporter PutP, putative; PFAM: Na+/solute symporter; SPTR: Na+/proline symporter PutP, putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.496 |
| AFZ47236.1 | AFZ47238.1 | Cyast_1271 | Cyast_1273 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR005924:IPR006035:IPR020855; KEGG: cyc:PCC7424_5245 agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; PRIAM: Agmatinase; SPTR: Arginase family; Belongs to the arginase family. | 0.681 |
| AFZ47236.1 | AFZ47518.1 | Cyast_1271 | Cyast_1557 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; COGs: COG0832 Urea amidohydrolase (urease) beta subunit; InterPro IPR002019; KEGG: mar:MAE_45230 urease beta subunit; PFAM: Urease beta subunit; PRIAM: Urease; SPTR: Urease subunit beta; TIGRFAM: urease, beta subunit. | 0.595 |
| AFZ47236.1 | hypA | Cyast_1271 | Cyast_1272 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.979 |
| AFZ47236.1 | ureA | Cyast_1271 | Cyast_0096 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | PFAM: Urease, gamma subunit; TIGRFAM: urease, gamma subunit; COGs: COG0831 Urea amidohydrolase (urease) gamma subunit; InterPro IPR012010:IPR002026; KEGG: cyc:PCC7424_4411 urease, gamma subunit; PFAM: Urease gamma subunit region; PRIAM: Urease; SPTR: Urease subunit gamma; TIGRFAM: urease, gamma subunit; Belongs to the urease gamma subunit family. | 0.686 |
| AFZ47236.1 | ureC | Cyast_1271 | Cyast_1956 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | PFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit; COGs: COG0804 Urea amidohydrolase (urease) alpha subunit; InterProIPR005848:IPR011612:IPR006680:IPR017950:IPR 017951:IPR017952; KEGG: mar:MAE_61330 urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain-containing protein; PRIAM: Urease; SPTR: Urease subunit alpha; TIGRFAM: urease, alpha subunit. | 0.688 |
| AFZ47236.1 | ureD | Cyast_1271 | Cyast_1164 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.738 |
| AFZ47236.1 | ureE | Cyast_1271 | Cyast_0095 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | UreE urease accessory domain-containing protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.830 |
| AFZ47236.1 | ureF | Cyast_1271 | Cyast_0094 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.924 |
| AFZ47238.1 | AFZ47235.1 | Cyast_1273 | Cyast_1270 | Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR005924:IPR006035:IPR020855; KEGG: cyc:PCC7424_5245 agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; PRIAM: Agmatinase; SPTR: Arginase family; Belongs to the arginase family. | PFAM: Sodium:solute symporter family; COGs: COG0591 Na+/proline symporter; InterPro IPR001734:IPR018212; KEGG: amr:AM1_1166 Na+/proline symporter PutP, putative; PFAM: Na+/solute symporter; SPTR: Na+/proline symporter PutP, putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.537 |
| AFZ47238.1 | AFZ47236.1 | Cyast_1273 | Cyast_1271 | Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR005924:IPR006035:IPR020855; KEGG: cyc:PCC7424_5245 agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; PRIAM: Agmatinase; SPTR: Arginase family; Belongs to the arginase family. | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | 0.681 |
| AFZ47238.1 | hypA | Cyast_1273 | Cyast_1272 | Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR005924:IPR006035:IPR020855; KEGG: cyc:PCC7424_5245 agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; PRIAM: Agmatinase; SPTR: Arginase family; Belongs to the arginase family. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.837 |
| AFZ47518.1 | AFZ47236.1 | Cyast_1557 | Cyast_1271 | PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; COGs: COG0832 Urea amidohydrolase (urease) beta subunit; InterPro IPR002019; KEGG: mar:MAE_45230 urease beta subunit; PFAM: Urease beta subunit; PRIAM: Urease; SPTR: Urease subunit beta; TIGRFAM: urease, beta subunit. | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | 0.595 |
| AFZ47518.1 | ureA | Cyast_1557 | Cyast_0096 | PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; COGs: COG0832 Urea amidohydrolase (urease) beta subunit; InterPro IPR002019; KEGG: mar:MAE_45230 urease beta subunit; PFAM: Urease beta subunit; PRIAM: Urease; SPTR: Urease subunit beta; TIGRFAM: urease, beta subunit. | PFAM: Urease, gamma subunit; TIGRFAM: urease, gamma subunit; COGs: COG0831 Urea amidohydrolase (urease) gamma subunit; InterPro IPR012010:IPR002026; KEGG: cyc:PCC7424_4411 urease, gamma subunit; PFAM: Urease gamma subunit region; PRIAM: Urease; SPTR: Urease subunit gamma; TIGRFAM: urease, gamma subunit; Belongs to the urease gamma subunit family. | 0.999 |
| AFZ47518.1 | ureC | Cyast_1557 | Cyast_1956 | PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; COGs: COG0832 Urea amidohydrolase (urease) beta subunit; InterPro IPR002019; KEGG: mar:MAE_45230 urease beta subunit; PFAM: Urease beta subunit; PRIAM: Urease; SPTR: Urease subunit beta; TIGRFAM: urease, beta subunit. | PFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit; COGs: COG0804 Urea amidohydrolase (urease) alpha subunit; InterProIPR005848:IPR011612:IPR006680:IPR017950:IPR 017951:IPR017952; KEGG: mar:MAE_61330 urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain-containing protein; PRIAM: Urease; SPTR: Urease subunit alpha; TIGRFAM: urease, alpha subunit. | 0.999 |
| AFZ47518.1 | ureD | Cyast_1557 | Cyast_1164 | PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; COGs: COG0832 Urea amidohydrolase (urease) beta subunit; InterPro IPR002019; KEGG: mar:MAE_45230 urease beta subunit; PFAM: Urease beta subunit; PRIAM: Urease; SPTR: Urease subunit beta; TIGRFAM: urease, beta subunit. | Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.944 |
| AFZ47518.1 | ureE | Cyast_1557 | Cyast_0095 | PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; COGs: COG0832 Urea amidohydrolase (urease) beta subunit; InterPro IPR002019; KEGG: mar:MAE_45230 urease beta subunit; PFAM: Urease beta subunit; PRIAM: Urease; SPTR: Urease subunit beta; TIGRFAM: urease, beta subunit. | UreE urease accessory domain-containing protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.922 |