| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFZ46774.1 | hypA | Cyast_0802 | Cyast_1272 | Rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin; COGs: COG1773 Rubredoxin; InterPro IPR004039:IPR018527:IPR001052; KEGG: cyh:Cyan8802_4189 rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin; Belongs to the rubredoxin family. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.436 |
| AFZ47235.1 | AFZ47236.1 | Cyast_1270 | Cyast_1271 | PFAM: Sodium:solute symporter family; COGs: COG0591 Na+/proline symporter; InterPro IPR001734:IPR018212; KEGG: amr:AM1_1166 Na+/proline symporter PutP, putative; PFAM: Na+/solute symporter; SPTR: Na+/proline symporter PutP, putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | 0.496 |
| AFZ47235.1 | AFZ47238.1 | Cyast_1270 | Cyast_1273 | PFAM: Sodium:solute symporter family; COGs: COG0591 Na+/proline symporter; InterPro IPR001734:IPR018212; KEGG: amr:AM1_1166 Na+/proline symporter PutP, putative; PFAM: Na+/solute symporter; SPTR: Na+/proline symporter PutP, putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR005924:IPR006035:IPR020855; KEGG: cyc:PCC7424_5245 agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; PRIAM: Agmatinase; SPTR: Arginase family; Belongs to the arginase family. | 0.537 |
| AFZ47235.1 | hypA | Cyast_1270 | Cyast_1272 | PFAM: Sodium:solute symporter family; COGs: COG0591 Na+/proline symporter; InterPro IPR001734:IPR018212; KEGG: amr:AM1_1166 Na+/proline symporter PutP, putative; PFAM: Na+/solute symporter; SPTR: Na+/proline symporter PutP, putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.549 |
| AFZ47236.1 | AFZ47235.1 | Cyast_1271 | Cyast_1270 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | PFAM: Sodium:solute symporter family; COGs: COG0591 Na+/proline symporter; InterPro IPR001734:IPR018212; KEGG: amr:AM1_1166 Na+/proline symporter PutP, putative; PFAM: Na+/solute symporter; SPTR: Na+/proline symporter PutP, putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.496 |
| AFZ47236.1 | AFZ47238.1 | Cyast_1271 | Cyast_1273 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR005924:IPR006035:IPR020855; KEGG: cyc:PCC7424_5245 agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; PRIAM: Agmatinase; SPTR: Arginase family; Belongs to the arginase family. | 0.681 |
| AFZ47236.1 | hypA | Cyast_1271 | Cyast_1272 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.979 |
| AFZ47238.1 | AFZ47235.1 | Cyast_1273 | Cyast_1270 | Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR005924:IPR006035:IPR020855; KEGG: cyc:PCC7424_5245 agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; PRIAM: Agmatinase; SPTR: Arginase family; Belongs to the arginase family. | PFAM: Sodium:solute symporter family; COGs: COG0591 Na+/proline symporter; InterPro IPR001734:IPR018212; KEGG: amr:AM1_1166 Na+/proline symporter PutP, putative; PFAM: Na+/solute symporter; SPTR: Na+/proline symporter PutP, putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.537 |
| AFZ47238.1 | AFZ47236.1 | Cyast_1273 | Cyast_1271 | Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR005924:IPR006035:IPR020855; KEGG: cyc:PCC7424_5245 agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; PRIAM: Agmatinase; SPTR: Arginase family; Belongs to the arginase family. | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | 0.681 |
| AFZ47238.1 | hypA | Cyast_1273 | Cyast_1272 | Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR005924:IPR006035:IPR020855; KEGG: cyc:PCC7424_5245 agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; PRIAM: Agmatinase; SPTR: Arginase family; Belongs to the arginase family. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.837 |
| AFZ48039.1 | hypA | Cyast_2089 | Cyast_1272 | Cobalamin (vitamin B12) biosynthesis CbiM protein; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: syn:sll0383 cobalt transport protein CbiM; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; SPTR: CbiM. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.431 |
| AFZ48056.1 | hypA | Cyast_2106 | Cyast_1272 | ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.659 |
| AFZ48112.1 | hypA | Cyast_2162 | Cyast_1272 | Lipopolysaccharide biosynthesis protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; COGs: COG0489 ATPase involved in chromosome partitioning; KEGG: cyp:PCC8801_2514 lipopolysaccharide biosynthesis protein; SPTR: Lipopolysaccharide biosynthesis protein. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.659 |
| AFZ48731.1 | hypA | Cyast_2789 | Cyast_1272 | PFAM: 4Fe-4S binding domain; Iron-Sulfur binding protein C terminal; COGs: COG1142 Fe-S-cluster-containing hydrogenase components 2; InterPro IPR017896:IPR017900; KEGG: cyh:Cyan8802_1231 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.600 |
| hypA | AFZ46774.1 | Cyast_1272 | Cyast_0802 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin; COGs: COG1773 Rubredoxin; InterPro IPR004039:IPR018527:IPR001052; KEGG: cyh:Cyan8802_4189 rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin; Belongs to the rubredoxin family. | 0.436 |
| hypA | AFZ47235.1 | Cyast_1272 | Cyast_1270 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | PFAM: Sodium:solute symporter family; COGs: COG0591 Na+/proline symporter; InterPro IPR001734:IPR018212; KEGG: amr:AM1_1166 Na+/proline symporter PutP, putative; PFAM: Na+/solute symporter; SPTR: Na+/proline symporter PutP, putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.549 |
| hypA | AFZ47236.1 | Cyast_1272 | Cyast_1271 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR004392:IPR003495; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB. | 0.979 |
| hypA | AFZ47238.1 | Cyast_1272 | Cyast_1273 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR005924:IPR006035:IPR020855; KEGG: cyc:PCC7424_5245 agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; PRIAM: Agmatinase; SPTR: Arginase family; Belongs to the arginase family. | 0.837 |
| hypA | AFZ48039.1 | Cyast_1272 | Cyast_2089 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Cobalamin (vitamin B12) biosynthesis CbiM protein; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: syn:sll0383 cobalt transport protein CbiM; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; SPTR: CbiM. | 0.431 |
| hypA | AFZ48056.1 | Cyast_1272 | Cyast_2106 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.659 |