node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFZ46781.1 | AFZ48781.1 | Cyast_0809 | Cyast_2841 | PFAM: Hsp70 protein; COGs: COG0443 Molecular chaperone; InterPro IPR018181:IPR013126:IPR001023; KEGG: cyc:PCC7424_0171 heat shock protein 70; PFAM: Heat shock protein 70; SPTR: Heat shock protein 70. | Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: syp:SYNPCC7002_A0654 small heat shock protein; PFAM: heat shock protein Hsp20; SPTR: Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | 0.481 |
AFZ46781.1 | clpB-2 | Cyast_0809 | Cyast_1793 | PFAM: Hsp70 protein; COGs: COG0443 Molecular chaperone; InterPro IPR018181:IPR013126:IPR001023; KEGG: cyc:PCC7424_0171 heat shock protein 70; PFAM: Heat shock protein 70; SPTR: Heat shock protein 70. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.775 |
AFZ46781.1 | grpE | Cyast_0809 | Cyast_2542 | PFAM: Hsp70 protein; COGs: COG0443 Molecular chaperone; InterPro IPR018181:IPR013126:IPR001023; KEGG: cyc:PCC7424_0171 heat shock protein 70; PFAM: Heat shock protein 70; SPTR: Heat shock protein 70. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.928 |
AFZ48781.1 | AFZ46781.1 | Cyast_2841 | Cyast_0809 | Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: syp:SYNPCC7002_A0654 small heat shock protein; PFAM: heat shock protein Hsp20; SPTR: Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | PFAM: Hsp70 protein; COGs: COG0443 Molecular chaperone; InterPro IPR018181:IPR013126:IPR001023; KEGG: cyc:PCC7424_0171 heat shock protein 70; PFAM: Heat shock protein 70; SPTR: Heat shock protein 70. | 0.481 |
AFZ48781.1 | clpB-2 | Cyast_2841 | Cyast_1793 | Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: syp:SYNPCC7002_A0654 small heat shock protein; PFAM: heat shock protein Hsp20; SPTR: Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.763 |
AFZ48781.1 | dnaK | Cyast_2841 | Cyast_1397 | Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: syp:SYNPCC7002_A0654 small heat shock protein; PFAM: heat shock protein Hsp20; SPTR: Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.481 |
AFZ48781.1 | dnaK-2 | Cyast_2841 | Cyast_2402 | Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: syp:SYNPCC7002_A0654 small heat shock protein; PFAM: heat shock protein Hsp20; SPTR: Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.481 |
AFZ48781.1 | dnaK-3 | Cyast_2841 | Cyast_2541 | Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: syp:SYNPCC7002_A0654 small heat shock protein; PFAM: heat shock protein Hsp20; SPTR: Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.481 |
AFZ48781.1 | grpE | Cyast_2841 | Cyast_2542 | Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: syp:SYNPCC7002_A0654 small heat shock protein; PFAM: heat shock protein Hsp20; SPTR: Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.631 |
clpB-2 | AFZ46781.1 | Cyast_1793 | Cyast_0809 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | PFAM: Hsp70 protein; COGs: COG0443 Molecular chaperone; InterPro IPR018181:IPR013126:IPR001023; KEGG: cyc:PCC7424_0171 heat shock protein 70; PFAM: Heat shock protein 70; SPTR: Heat shock protein 70. | 0.775 |
clpB-2 | AFZ48781.1 | Cyast_1793 | Cyast_2841 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: syp:SYNPCC7002_A0654 small heat shock protein; PFAM: heat shock protein Hsp20; SPTR: Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | 0.763 |
clpB-2 | clpP | Cyast_1793 | Cyast_1413 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.812 |
clpB-2 | clpP-2 | Cyast_1793 | Cyast_2287 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.812 |
clpB-2 | clpP-3 | Cyast_1793 | Cyast_2288 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.812 |
clpB-2 | clpP-4 | Cyast_1793 | Cyast_2299 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.812 |
clpB-2 | dnaK | Cyast_1793 | Cyast_1397 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.936 |
clpB-2 | dnaK-2 | Cyast_1793 | Cyast_2402 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.890 |
clpB-2 | dnaK-3 | Cyast_1793 | Cyast_2541 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.936 |
clpB-2 | grpE | Cyast_1793 | Cyast_2542 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.855 |
clpP | clpB-2 | Cyast_1413 | Cyast_1793 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.812 |