Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFZ47916.1Cobalamin (vitamin B12) biosynthesis CbiX protein; PFAM: CbiX; COGs: COG2138 conserved hypothetical protein; InterPro IPR002762; KEGG: cyc:PCC7424_3112 cobalamin (vitamin B12) biosynthesis CbiX protein; PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiX protein. (243 aa)    
Predicted Functional Partners:
AFZ47257.1
Precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase; COGs: COG2243 Precorrin-2 methylase; InterPro IPR012382:IPR006364:IPR000878; KEGG: cyc:PCC7424_4665 precorrin-2 methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Precorrin-2 C20-methyltransferase; TIGRFAM: precorrin-2 C20-methyltransferase; cobalt-factor II C20-methyltransferase.
 
  
 0.957
AFZ46122.1
Cobalamin (vitamin B12) biosynthesis CbiX protein; PFAM: CbiX; COGs: COG2138 conserved hypothetical protein; InterPro IPR007087:IPR002762; KEGG: cyh:Cyan8802_3890 cobalamin (vitamin B12) biosynthesis CbiX protein; PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiX protein.
  
  
 
0.924
AFZ47915.1
KEGG: syp:SYNPCC7002_A0524 hypothetical protein; SPTR: Conserved hypothetical membrane protein.
       0.773
AFZ47950.1
Precorrin-3 methyltransferase; PFAM: Cobalamin synthesis G C-terminus; Cobalamin biosynthesis central region; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; TIGRFAM: precorrin-3B C17-methyltransferase; COGs: COG1010 Precorrin-3B methylase; InterPro IPR006363:IPR002750:IPR000878; KEGG: cyc:PCC7424_0379 precorrin-3B C17-methyltransferase; PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Precorrin-3B C(17)-methyltransferase; SPTR: Precorrin-3B C17-methyltransferase; TIGRFAM: [...]
 
   
 0.734
AFZ48508.1
PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR006365:IPR000878:IPR012818:IPR014008; KEGG: cyh:Cyan8802_1505 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE s [...]
 
   
 0.719
AFZ47914.1
KEGG: bhy:BHWA1_01992 hypothetical protein; SPTR: Hypotheical protein.
       0.566
AFZ48703.1
uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878:IPR003043:IPR006366; KEGG: cyc:PCC7424_1682 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Uroporphyrinogen-III C-methyltransferase; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 0.508
AFZ47690.1
PFAM: Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: cyc:PCC7424_5060 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; SPTR: Precorrin-8X methylmutase CbiC/CobH.
 
   
 0.496
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
   
 0.486
AFZ47917.1
PFAM: Cytochrome oxidase subunit II; TIGRFAM: cytochrome d oxidase, subunit II (cydB); COGs: COG1294 Cytochrome bd-type quinol oxidase subunit 2; InterPro IPR003317; KEGG: cyn:Cyan7425_3998 cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; SPTR: Cytochrome bd ubiquinol oxidase, subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II.
  
    0.462
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
Server load: low (14%) [HD]