STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ48220.1PFAM: ABC transporter; ABC transporter transmembrane region 2; COGs: COG4178 ABC-type uncharacterized transport system permease and ATPase components; InterProIPR017871:IPR010509:IPR003439:IPR017940:IPR 003593; KEGG: cyc:PCC7424_5296 ABC transporter domain protein; PFAM: ABC transporter domain-containing protein; ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter domain protein. (564 aa)    
Predicted Functional Partners:
AFZ48221.1
PFAM: Protein of unknown function (DUF3086); KEGG: cyc:PCC7424_5081 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
    
   0.631
AFZ48222.1
PFAM: Protein of unknown function (DUF3119); KEGG: ter:Tery_3052 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.618
AFZ47015.1
AAA ATPase central domain protein; PFAM: ATPase family associated with various cellular activities (AAA); COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR003959; KEGG: cyh:Cyan8802_3458 AAA ATPase central domain protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase central domain protein.
     
 0.617
AFZ48779.1
AAA ATPase central domain protein; PFAM: ATPase family associated with various cellular activities (AAA); COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003959:IPR003593; KEGG: cyt:cce_3437 ATPase; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: ATPase.
     
 0.617
AFZ46264.1
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: AMP-dependent synthetase and ligase; SPTR: Beta-ketoacyl synthase.
      
 0.542
AFZ46265.1
Beta-ketoacyl synthase; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, N-terminal domain; AMP-binding enzyme; Sulfotransferase domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR000639:IPR009081:IPR006162:IPR018201:IPR 000873:IPR006163:IPR014030:IPR014031:IPR014043:IPR013968:I PR000863:IPR000073; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; phosphopantetheine-binding; AMP-dependent synthetase and ligase; Acyl transferase; KR do [...]
      
 0.542
proA-2
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
  
   0.439
AFZ46871.1
PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR018211:IPR015590:IPR001670:IPR012079; KEGG: mar:MAE_49340 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; SPTR: Alcohol dehydrogenase, iron-containing family; alcohol dehydrogenase AdhE; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
   
 
  0.424
AFZ48453.1
PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR002872:IPR015590:IPR016160:IPR005932; KEGG: cyc:PCC7424_1002 delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; SPTR: Delta-1-pyrroline-5-carboxylate dehydrogenase; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; L-proline dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
  0.402
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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