node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFZ47413.1 | AFZ48403.1 | Cyast_1449 | Cyast_2459 | PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR001789:IPR004358:IPR013767:IPR016132:I PR005467:IPR000700; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CBS domain containing protein; PAS fold domain pro [...] | ATPase AAA-2 domain protein; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; UvrB/uvrC motif; ATPase family associated with various cellular activities (AAA); COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR001943:IPR004176:IPR003959:IPR 013093:IPR019489:IPR018368:IPR001270; KEGG: cyp:PCC8801_1419 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPase AAA-2 [...] | 0.579 |
AFZ47413.1 | clpB | Cyast_1449 | Cyast_0149 | PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR001789:IPR004358:IPR013767:IPR016132:I PR005467:IPR000700; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CBS domain containing protein; PAS fold domain pro [...] | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.579 |
AFZ47413.1 | clpB-2 | Cyast_1449 | Cyast_1793 | PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR001789:IPR004358:IPR013767:IPR016132:I PR005467:IPR000700; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CBS domain containing protein; PAS fold domain pro [...] | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.579 |
AFZ47413.1 | clpP-2 | Cyast_1449 | Cyast_2287 | PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR001789:IPR004358:IPR013767:IPR016132:I PR005467:IPR000700; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CBS domain containing protein; PAS fold domain pro [...] | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.531 |
AFZ47413.1 | clpP-3 | Cyast_1449 | Cyast_2288 | PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR001789:IPR004358:IPR013767:IPR016132:I PR005467:IPR000700; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CBS domain containing protein; PAS fold domain pro [...] | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.531 |
AFZ47413.1 | clpX | Cyast_1449 | Cyast_2300 | PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR001789:IPR004358:IPR013767:IPR016132:I PR005467:IPR000700; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CBS domain containing protein; PAS fold domain pro [...] | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.504 |
AFZ47413.1 | hrcA | Cyast_1449 | Cyast_2811 | PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR001789:IPR004358:IPR013767:IPR016132:I PR005467:IPR000700; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CBS domain containing protein; PAS fold domain pro [...] | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.469 |
AFZ48403.1 | AFZ47413.1 | Cyast_2459 | Cyast_1449 | ATPase AAA-2 domain protein; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; UvrB/uvrC motif; ATPase family associated with various cellular activities (AAA); COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR001943:IPR004176:IPR003959:IPR 013093:IPR019489:IPR018368:IPR001270; KEGG: cyp:PCC8801_1419 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPase AAA-2 [...] | PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR001789:IPR004358:IPR013767:IPR016132:I PR005467:IPR000700; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CBS domain containing protein; PAS fold domain pro [...] | 0.579 |
AFZ48403.1 | clpP-2 | Cyast_2459 | Cyast_2287 | ATPase AAA-2 domain protein; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; UvrB/uvrC motif; ATPase family associated with various cellular activities (AAA); COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR001943:IPR004176:IPR003959:IPR 013093:IPR019489:IPR018368:IPR001270; KEGG: cyp:PCC8801_1419 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPase AAA-2 [...] | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.780 |
AFZ48403.1 | clpP-3 | Cyast_2459 | Cyast_2288 | ATPase AAA-2 domain protein; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; UvrB/uvrC motif; ATPase family associated with various cellular activities (AAA); COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR001943:IPR004176:IPR003959:IPR 013093:IPR019489:IPR018368:IPR001270; KEGG: cyp:PCC8801_1419 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPase AAA-2 [...] | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.769 |
AFZ48403.1 | clpS | Cyast_2459 | Cyast_1098 | ATPase AAA-2 domain protein; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; UvrB/uvrC motif; ATPase family associated with various cellular activities (AAA); COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR001943:IPR004176:IPR003959:IPR 013093:IPR019489:IPR018368:IPR001270; KEGG: cyp:PCC8801_1419 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPase AAA-2 [...] | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.678 |
AFZ48403.1 | hrcA | Cyast_2459 | Cyast_2811 | ATPase AAA-2 domain protein; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; UvrB/uvrC motif; ATPase family associated with various cellular activities (AAA); COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR001943:IPR004176:IPR003959:IPR 013093:IPR019489:IPR018368:IPR001270; KEGG: cyp:PCC8801_1419 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPase AAA-2 [...] | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.473 |
clpB | AFZ47413.1 | Cyast_0149 | Cyast_1449 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR001789:IPR004358:IPR013767:IPR016132:I PR005467:IPR000700; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CBS domain containing protein; PAS fold domain pro [...] | 0.579 |
clpB | clpP-2 | Cyast_0149 | Cyast_2287 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.812 |
clpB | clpP-3 | Cyast_0149 | Cyast_2288 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.812 |
clpB | clpS | Cyast_0149 | Cyast_1098 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.769 |
clpB | clpX | Cyast_0149 | Cyast_2300 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.612 |
clpB | hrcA | Cyast_0149 | Cyast_2811 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.473 |
clpB-2 | AFZ47413.1 | Cyast_1793 | Cyast_1449 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR001789:IPR004358:IPR013767:IPR016132:I PR005467:IPR000700; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CBS domain containing protein; PAS fold domain pro [...] | 0.579 |
clpB-2 | clpP-2 | Cyast_1793 | Cyast_2287 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.812 |