STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ48259.1PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR010372:IPR005790; KEGG: cyc:PCC7424_3459 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta; SPTR: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit. (324 aa)    
Predicted Functional Partners:
AFZ46342.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.998
AFZ47774.1
DNA polymerase III, delta prime subunit; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: cyc:PCC7424_3164 DNA polymerase III subunit delta'; SPTR: DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit.
  
 
 0.998
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.998
AFZ46491.1
PFAM: OB-fold nucleic acid binding domain; TIGRFAM: intein C-terminal splicing region; COGs: COG0587 DNA polymerase III alpha subunit; InterPro IPR004365:IPR006141; KEGG: cyh:Cyan8802_3770 nucleic acid binding OB-fold tRNA/helicase-type; PFAM: nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Nucleic acid binding OB-fold tRNA/helicase-type.
   
 0.989
AFZ47222.1
PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; TIGRFAM: intein N-terminal splicing region; DNA-directed DNA polymerase III (polc); COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR003141:IPR003587:IPR004805:IPR006141:IPR 004013:IPR011708; KEGG: cyh:Cyan8802_3682 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; Hedgehog/intein hint domain protein; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit.
   
 0.989
queC
preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
       0.727
AFZ46903.1
KEGG: mar:MAE_35130 transcriptional regulator; SPTR: Transcriptional regulator.
  
     0.631
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.630
AFZ46578.1
PFAM: Cytochrome c; InterPro IPR003088:IPR009056; KEGG: cyt:cce_3264 cytochrome cM; PFAM: cytochrome c class I; SPTR: Cytochrome cM.
  
     0.620
ndhO
Component of NDH complex; NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
  
     0.586
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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