STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ48423.1Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (87 aa)    
Predicted Functional Partners:
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
  
 0.915
AFZ46704.1
PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708:IPR020001; KEGG: cyc:PCC7424_0894 putative inner membrane protein translocase component YidC; PFAM: 60 kDa inner membrane insertion protein; SPTR: 60 kDa inner membrane insertion protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; manually curated.
  
  
 0.784
AFZ48422.1
PFAM: Domain of unknown function (DUF1817); COGs: COG5474 conserved hypothetical protein; InterPro IPR014946; KEGG: cyc:PCC7424_2381 hypothetical protein; PFAM: Domain of unknown function DUF1817; SPTR: Putative uncharacterized protein.
       0.773
secE
Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
   
    0.735
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
    0.718
AFZ46564.1
Peptidase M15D vanX D-ala-D-ala dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.
      0.670
AFZ46056.1
Methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: syp:SYNPCC7002_A0020 methyltransferase, putative; PFAM: Conserved hypothetical protein CHP00095; SPTR: Methyltransferase, putative; TIGRFAM: methyltransferase.
  
    0.654
AFZ46705.1
PFAM: R3H domain; COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: cyc:PCC7424_0893 single-stranded nucleic acid binding R3H domain protein; PFAM: single-stranded nucleic acid binding R3H domain-containing protein; SMART: single-stranded nucleic acid binding R3H domain-containing protein; SPTR: Single-stranded nucleic acid binding R3H domain protein.
  
    0.609
rplB
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
    0.558
AFZ48421.1
FAD dependent oxidoreductase; COGs: COG0644 Dehydrogenase (flavoprotein); KEGG: mar:MAE_54440 FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase.
       0.557
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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