STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ48486.1PFAM: Peptidase family M1; PBS lyase HEAT-like repeat; COGs: COG0308 Aminopeptidase N; InterPro IPR004155:IPR014782; KEGG: cyc:PCC7424_4277 peptidase M1 membrane alanine aminopeptidase; PFAM: Peptidase M1 membrane alanine aminopeptidase; PBS lyase HEAT domain protein repeat-containing protein; SPTR: HEAT:Peptidase M1, membrane alanine aminopeptidase:PBS lyase HEAT-like repeat. (857 aa)    
Predicted Functional Partners:
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 0.975
gshB
PFAM: Prokaryotic glutathione synthetase, N-terminal domain; Prokaryotic glutathione synthetase, ATP-grasp domain; TIGRFAM: glutathione synthetase, prokaryotic; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR004215:IPR004218:IPR011761:IPR006284; KEGG: ter:Tery_4206 glutathione synthetase; PFAM: glutathione synthetase ATP-binding; glutathione synthetase domain protein; PRIAM: Glutathione synthase; SPTR: Glutathione synthetase; TIGRFAM: glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
     
 0.901
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.849
AFZ46126.1
Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase.
     
 0.817
AFZ47630.1
Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR001216:IPR005856:IPR005859; KEGG: cyc:PCC7424_1502 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
     
 0.817
AFZ48003.1
PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR004838:IPR000425:IPR001176; KEGG: ava:Ava_2127 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase.
   
 
 0.804
AFZ46455.1
PFAM: Serpin (serine protease inhibitor); COGs: COG4826 Serine protease inhibitor; InterPro IPR000215; KEGG: ana:all0778 hypothetical protein; PFAM: proteinase inhibitor I4 serpin; SMART: proteinase inhibitor I4 serpin; SPTR: All0778 protein.
   
 0.634
AFZ48292.1
PFAM: Peptidase family M48; InterPro IPR001915; KEGG: cyh:Cyan8802_2623 peptidase M56 BlaR1; PFAM: peptidase M48 Ste24p; SPTR: Peptidase M56 BlaR1.
  
   
 0.580
AFZ46468.1
KEGG: cyp:PCC8801_0555 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.574
AFZ46264.1
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: AMP-dependent synthetase and ligase; SPTR: Beta-ketoacyl synthase.
  
 
 0.554
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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