STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menGDemethylmenaquinone methyltransferase; Methyltransferase required for the conversion of 2-phytyl- 1,4-beta-naphthoquinol to phylloquinol. (235 aa)    
Predicted Functional Partners:
AFZ46009.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: cyt:cce_0154 type 2 NADH dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
     
  0.900
AFZ47360.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: mar:MAE_62400 type 2 NADH dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
     
  0.900
menB
1,4-Dihydroxy-2-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
   
 0.780
menA
1,4-dihydroxy-2-naphthoate phytyltransferase; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone; Belongs to the MenA family. Type 2 subfamily.
 
  
 0.594
AFZ48494.1
PFAM: Aldo/keto reductase family; COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395:IPR018170; KEGG: cyh:Cyan8802_0017 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase.
  
    0.508
AFZ46264.1
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: AMP-dependent synthetase and ligase; SPTR: Beta-ketoacyl synthase.
   
 
 0.506
AFZ46265.1
Beta-ketoacyl synthase; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, N-terminal domain; AMP-binding enzyme; Sulfotransferase domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR000639:IPR009081:IPR006162:IPR018201:IPR 000873:IPR006163:IPR014030:IPR014031:IPR014043:IPR013968:I PR000863:IPR000073; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; phosphopantetheine-binding; AMP-dependent synthetase and ligase; Acyl transferase; KR do [...]
   
 
 0.506
AFZ48496.1
PFAM: Protein of unknown function (DUF445); COGs: COG4399 conserved hypothetical protein; InterPro IPR016991:IPR007383; KEGG: cyc:PCC7424_0748 protein of unknown function DUF445; PFAM: protein of unknown function DUF445; SPTR: UPF0754 membrane protein PCC7424_0748; Belongs to the UPF0754 family.
       0.474
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.