STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ48562.1Thiamine S protein; PFAM: ThiS family; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal; COGs: COG1977 Molybdopterin converting factor small subunit; InterPro IPR003749; KEGG: mar:MAE_08100 thiamineS; PFAM: thiamineS protein; SPTR: Similar to tr|Q8YP47|Q8YP47. (88 aa)    
Predicted Functional Partners:
AFZ46517.1
PFAM: MoaE protein; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: cyc:PCC7424_2740 molybdopterin biosynthesis MoaE protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Molybdopterin biosynthesis MoaE protein.
 
 0.997
AFZ47564.1
UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; Rhodanese-like domain; ThiF family; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR007901:IPR001763; KEGG: ava:Ava_0994 hypothetical protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Molybdopterin biosynthesis protein MoeB.
  
 0.982
AFZ47677.1
Molybdopterin synthase subunit MoaD; PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal; COGs: COG1977 Molybdopterin converting factor small subunit; InterPro IPR003749:IPR010038; KEGG: cyt:cce_2444 thiamineS-like protein; PFAM: thiamineS protein; SPTR: Similar to Cter of sp|P74060|Y821_SYNY3 UPF0084 protein slr0821; TIGRFAM: MoaD family protein.
  
  
  0.911
moaC
GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
  
 0.785
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
   
 
 0.777
AFZ46831.1
Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.664
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
  
 0.611
AFZ46778.1
Molybdenum cofactor synthesis domain protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.
 
  
 0.545
AFZ48563.1
Hypothetical protein; InterPro IPR020885; KEGG: cyp:PCC8801_1959 hypothetical protein; SPTR: UPF0367 protein PCC8801_1959; Belongs to the UPF0367 family.
       0.528
gcvP
Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
    0.512
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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