STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ48606.1PFAM: Ferric uptake regulator family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: syp:SYNPCC7002_A2498 ferric uptake regulation protein; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulation protein; Belongs to the Fur family. (131 aa)    
Predicted Functional Partners:
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
      
 0.733
AFZ47660.1
Transport system permease protein; PFAM: FecCD transport family; COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: amr:AM1_3414 iron compound ABC transporter, permease protein, putative; PFAM: transport system permease protein; SPTR: Iron compound ABC transporter, permease protein, putative; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
      
 0.710
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.592
AFZ47553.1
PFAM: Bacterial regulatory protein, arsR family; TIGRFAM: iron-sulfur cluster biosynthesis transcriptional regulator SufR; COGs: COG2345 transcriptional regulator protein; InterPro IPR001845:IPR014075; KEGG: cyh:Cyan8802_0425 putative transcriptional regulator; PFAM: regulatory protein ArsR; SPTR: Putative transcriptional regulator; TIGRFAM: iron-sulfur cluster biosynthesis transcriptional regulator SufR.
 
    0.558
AFZ48607.1
Putative CheA signal transduction histidine kinase; PFAM: CheW-like domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR003594:IPR002545:IPR001789:IPR005467:IPR 004105:IPR004358; KEGG: cyh:Cyan8802_3559 putative CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; CheW domain protein; response regulator receiver; SMA [...]
   
 
 0.554
AFZ48605.1
Metallothionein family 14; PFAM: Prokaryotic metallothionein; InterPro IPR000518; KEGG: cyc:PCC7424_2545 metallothionein family 14; PFAM: metallothionein family 14; SPTR: Metallothionein.
     
 0.551
AFZ47413.1
PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR001789:IPR004358:IPR013767:IPR016132:I PR005467:IPR000700; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CBS domain containing protein; PAS fold domain pro [...]
   
 
 0.479
AFZ46585.1
Glutamate synthase (NADH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583:IPR006982:IPR002932:IPR002489:IPR 017932; KEGG: cyc:PCC7424_3654 glutamate synthase (ferredoxin); PFAM: glutamine amidotransferase class-II; glutamate synthase; ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin).
     
 0.448
AFZ46889.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932:IPR000583:IPR006982:IPR002932:IPR 002489; KEGG: cyp:PCC8801_3730 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin).
     
 0.448
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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