STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ48641.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (118 aa)    
Predicted Functional Partners:
AFZ47307.1
PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: cyt:cce_2591 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrop [...]
 
 
 0.997
AFZ46973.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.988
folE-2
PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; COGs: COG0302 GTP cyclohydrolase I; InterPro IPR001474:IPR020602:IPR018234; KEGG: cyh:Cyan8802_0939 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
 
  
 0.844
folE
PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; COGs: COG0302 GTP cyclohydrolase I; InterPro IPR001474:IPR020602:IPR018234; KEGG: cyc:PCC7424_3847 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
 
  
 0.841
AFZ48241.1
Hypothetical protein; InterPro IPR017260; KEGG: cyp:PCC8801_2583 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.785
AFZ46196.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.679
AFZ48455.1
FolC bifunctional protein; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221:IPR004101:IPR018109:IPR001645; KEGG: mar:MAE_15990 folylpolyglutamate synthase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; PRIAM: Tetrahydrofolate synthase; SPTR: FolC bifunctional protein; TIGRFAM: FolC bifunctional protein.
  
  
 0.572
AFZ46326.1
Para-aminobenzoate synthase, subunit I; PFAM: Glutamine amidotransferase class-I; chorismate binding enzyme; Anthranilate synthase component I, N terminal region; TIGRFAM: aminodeoxychorismate synthase, fungal clade; glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase; aminodeoxychorismate synthase, component I, bacterial clade; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterProIPR000991:IPR006805:IPR015890:IPR017926:IPR 006220:IPR011702:IPR001317:IPR006221:IPR005802; KEGG: npu:Npun_R3717 para-aminobenzoate synthase, subunit I; [...]
 
  
 0.569
AFZ48640.1
Protein of unknown function YGGT; PFAM: YGGT family; InterPro IPR003425; KEGG: cyc:PCC7424_3030 protein of unknown function YGGT; PFAM: protein of unknown function YGGT; SPTR: Putative uncharacterized protein.
  
    0.554
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.483
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.