STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ48763.1Putative transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: cyt:cce_4162 hypothetical protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Putative uncharacterized protein. (123 aa)    
Predicted Functional Partners:
AFZ48090.1
Diguanylate cyclase with PAS/PAC and GAF sensors; PFAM: Protein kinase domain; GGDEF domain; GAF domain; NB-ARC domain; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG3899 ATPase; InterProIPR017442:IPR003018:IPR013767:IPR000160:IPR 000719:IPR000014:IPR000700:IPR020635:IPR002290; KEGG: mar:MAE_22800 serine/threonine kinase; PFAM: GGDEF domain containing protein; Serine/threonine-protein kinase-like domain; GAF domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domai [...]
  
 0.776
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
  
 0.775
AFZ48765.1
PFAM: Phosphoglycerate mutase family; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078:IPR001345; KEGG: cyt:cce_2454 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase.
 
 
   0.610
AFZ48818.1
PFAM: Protein of unknown function (DUF3539); KEGG: cyt:cce_2716 hypothetical protein; SPTR: Putative uncharacterized protein.
    
 0.605
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.588
AFZ47413.1
PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR001789:IPR004358:IPR013767:IPR016132:I PR005467:IPR000700; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CBS domain containing protein; PAS fold domain pro [...]
  
 
 0.585
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.575
AFZ46364.1
Multi-sensor hybrid histidine kinase; PFAM: CBS domain; Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000644:IPR003018:IPR013655:IPR013656:IPR 003661:IPR003594:IPR001789:IPR016132:IPR005467:IPR000014:I PR000700:IPR004358:IPR001610; KEGG: ava:Ava_4701 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; CB [...]
   
 
 0.514
AFZ48646.1
PFAM: Protein of unknown function (DUF721); COGs: COG5512 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives; InterPro IPR007922; KEGG: cyh:Cyan8802_1595 protein of unknown function DUF721; PFAM: protein of unknown function DUF721; SPTR: Putative uncharacterized protein.
  
     0.509
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
       0.493
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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