STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (404 aa)    
Predicted Functional Partners:
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.947
AFZ47683.1
PFAM: DRTGG domain; COGs: COG0857 BioD-like N-terminal domain of phosphotransacetylase; InterPro IPR010766:IPR019825; KEGG: cyt:cce_0822 hypothetical protein; PFAM: DRTGG domain protein; SPTR: Putative uncharacterized protein.
 
  
 0.925
AFZ46438.1
PFAM: Aldehyde dehydrogenase family; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR012394:IPR016160; KEGG: ava:Ava_3615 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.919
AFZ48763.1
Putative transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: cyt:cce_4162 hypothetical protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Putative uncharacterized protein.
  
  
 0.775
AFZ47976.1
Phosphoketolase; PFAM: XFP N-terminal domain; D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; XFP C-terminal domain; COGs: COG3957 Phosphoketolase; InterProIPR005593:IPR018970:IPR018969:IPR019790:IPR 019789; KEGG: cyc:PCC7424_3782 putative phosphoketolase; PFAM: Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase-like; D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; PRIAM: Phosphoketolase; SPTR: Phosphoketolase.
  
 0.712
AFZ46264.1
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: AMP-dependent synthetase and ligase; SPTR: Beta-ketoacyl synthase.
  
  
 0.644
AFZ46265.1
Beta-ketoacyl synthase; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, N-terminal domain; AMP-binding enzyme; Sulfotransferase domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR000639:IPR009081:IPR006162:IPR018201:IPR 000873:IPR006163:IPR014030:IPR014031:IPR014043:IPR013968:I PR000863:IPR000073; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; phosphopantetheine-binding; AMP-dependent synthetase and ligase; Acyl transferase; KR do [...]
  
  
 0.644
AFZ46496.1
PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; COGs: COG0469 Pyruvate kinase; InterPro IPR015793:IPR015794:IPR008279:IPR001697; KEGG: cyc:PCC7424_3440 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 0.630
sfsA
PFAM: Sugar fermentation stimulation protein; TIGRFAM: sugar fermentation stimulation protein; COGs: COG1489 DNA-binding protein stimulates sugar fermentation; InterPro IPR005224; KEGG: cyt:cce_2616 sugar fermentation stimulation protein; PFAM: sugar fermentation stimulation protein; SPTR: Sugar fermentation stimulation protein homolog; TIGRFAM: sugar fermentation stimulation protein; Belongs to the SfsA family.
 
      0.614
AFZ48765.1
PFAM: Phosphoglycerate mutase family; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078:IPR001345; KEGG: cyt:cce_2454 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase.
     
 0.603
Your Current Organism:
Cyanobacterium stanieri
NCBI taxonomy Id: 292563
Other names: C. stanieri PCC 7202, Cyanobacterium stanieri PCC 7202, Synechococcus cedrorum CCAP 14792a (no longer available), Synechococcus cedrorum CCAP 14792b (no longer available), Synechococcus cedrorum M137/1a, Synechococcus cedrorum SAG 88.79, Synechococcus sp. ATCC 29140, Synechococcus sp. PCC 7202
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