STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANU42105.2Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (248 aa)    
Predicted Functional Partners:
ANU42106.1
SpoIVB peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.982
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
  
 0.820
ANU41247.1
Stage IV sporulation protein A; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.813
ANU40882.1
Sporulation sigma factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.812
ANU41424.1
Sporulation sigma factor SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.802
ANU42133.1
Stage V sporulation protein T; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.797
ANU41616.1
Stage V sporulation protein AD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.785
ANU42842.1
Sporulation transcriptional regulator SpoIIID; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.767
ANU40487.1
Stage V sporulation protein AC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.760
ANU41934.1
RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family.
  
  
 0.744
Your Current Organism:
Flavonifractor plautii
NCBI taxonomy Id: 292800
Other names: ATCC 29863, ATCC 49531 [[Clostridium orbiscindens]], Bacillus plauti, CCUG 28093, Clostridium orbiscindens, DSM 4000, DSM 6740 [[Clostridium orbiscindens]], DSM 6749 [[Clostridium orbiscindens]], Eubacterium plautii, F. plautii, Fusobacterium plautii, Fusocillus plauti, Pseudoflavonifractor sp. YL31, Zuberella plauti, strain Prevot S1
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