STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANU42176.1Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response). (205 aa)    
Predicted Functional Partners:
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.968
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
 
 0.890
ANU42174.1
Cupin; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.762
ANU42175.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.737
ANU42963.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.659
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
      
 0.459
cinA
Competence/damage-inducible protein A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
     
 0.440
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
  
   
 0.437
ANU39634.1
Sodium:solute symporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.401
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.400
Your Current Organism:
Flavonifractor plautii
NCBI taxonomy Id: 292800
Other names: ATCC 29863, ATCC 49531 [[Clostridium orbiscindens]], Bacillus plauti, CCUG 28093, Clostridium orbiscindens, DSM 4000, DSM 6740 [[Clostridium orbiscindens]], DSM 6749 [[Clostridium orbiscindens]], Eubacterium plautii, F. plautii, Fusobacterium plautii, Fusocillus plauti, Pseudoflavonifractor sp. YL31, Zuberella plauti, strain Prevot S1
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