node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Wbm0124 | polA | Wbm0124 | Wbm0725 | Single-stranded DNA-specific exonuclease RecJ. | DNA polymerase I, PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.477 |
Wbm0124 | recA | Wbm0124 | Wbm0427 | Single-stranded DNA-specific exonuclease RecJ. | RecA recombinase; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.416 |
Wbm0124 | recF | Wbm0124 | Wbm0126 | Single-stranded DNA-specific exonuclease RecJ. | Recombinational DNA repair ATPase, RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.474 |
Wbm0124 | ruvA | Wbm0124 | Wbm0251 | Single-stranded DNA-specific exonuclease RecJ. | Holliday junction resolvasome, DNA-binding subunit, RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.448 |
Wbm0124 | ruvB | Wbm0124 | Wbm0252 | Single-stranded DNA-specific exonuclease RecJ. | Holliday junction resolvasome, helicase subunit, RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.465 |
Wbm0124 | ruvC | Wbm0124 | Wbm0697 | Single-stranded DNA-specific exonuclease RecJ. | Holliday junction resolvasome, endonuclease subunit, RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.575 |
Wbm0124 | topA | Wbm0124 | Wbm0037 | Single-stranded DNA-specific exonuclease RecJ. | Topoisomerase IA, TopA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA s [...] | 0.531 |
Wbm0698 | ruvC | Wbm0698 | Wbm0697 | Cytochrome c oxidase, subunit 3. | Holliday junction resolvasome, endonuclease subunit, RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.827 |
cysS | polA | Wbm0680 | Wbm0725 | Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA polymerase I, PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.618 |
cysS | recA | Wbm0680 | Wbm0427 | Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | RecA recombinase; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.421 |
cysS | ruvA | Wbm0680 | Wbm0251 | Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Holliday junction resolvasome, DNA-binding subunit, RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.448 |
cysS | ruvC | Wbm0680 | Wbm0697 | Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Holliday junction resolvasome, endonuclease subunit, RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.448 |
def | ruvC | Wbm0114 | Wbm0697 | N-formylmethionyl-tRNA deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Holliday junction resolvasome, endonuclease subunit, RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.532 |
polA | Wbm0124 | Wbm0725 | Wbm0124 | DNA polymerase I, PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Single-stranded DNA-specific exonuclease RecJ. | 0.477 |
polA | cysS | Wbm0725 | Wbm0680 | DNA polymerase I, PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.618 |
polA | recA | Wbm0725 | Wbm0427 | DNA polymerase I, PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | RecA recombinase; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.998 |
polA | recF | Wbm0725 | Wbm0126 | DNA polymerase I, PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Recombinational DNA repair ATPase, RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.617 |
polA | ruvA | Wbm0725 | Wbm0251 | DNA polymerase I, PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Holliday junction resolvasome, DNA-binding subunit, RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.638 |
polA | ruvB | Wbm0725 | Wbm0252 | DNA polymerase I, PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Holliday junction resolvasome, helicase subunit, RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.617 |
polA | ruvC | Wbm0725 | Wbm0697 | DNA polymerase I, PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Holliday junction resolvasome, endonuclease subunit, RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.663 |