Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ORV72679.1Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (600 aa)    
Predicted Functional Partners:
ORV71213.1
3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.940
fabH
3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
    
 0.807
ORV72005.1
acetyl-/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.804
ORV69142.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.803
ORV69366.1
propionyl-CoA carboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.802
ORV70436.1
Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.800
ORV67944.1
acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
0.684
ORV69566.1
AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
0.680
ORV70723.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 
0.679
ORV67958.1
acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
0.668
Your Current Organism:
Mycolicibacter hiberniae
NCBI taxonomy Id: 29314
Other names: ATCC 49874, ATCC 9874, CIP 104537, DSM 44241, JCM 13571, M. hiberniae, Mycobacterium hiberniae, Mycobacterium hiberniense, strain Hi 11
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