STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORV69624.1Protease 2; PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; Derived by automated computational analysis using gene prediction method: Protein Homology. (708 aa)    
Predicted Functional Partners:
clpP-2
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.874
purC
Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family.
       0.873
ORV69623.1
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family.
       0.807
ORV69622.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.772
ORV68699.1
Nucleoid-associated protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
  
 0.743
ORV72521.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.669
ORV69621.1
Deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.647
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.589
ORV69620.1
FAD-binding dehydrogenase; Proposed role in polysaccahride synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.549
ORV69626.1
Endoglycoceramidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.534
Your Current Organism:
Mycolicibacter hiberniae
NCBI taxonomy Id: 29314
Other names: ATCC 49874, ATCC 9874, CIP 104537, DSM 44241, JCM 13571, M. hiberniae, Mycobacterium hiberniae, Mycobacterium hiberniense, strain Hi 11
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