Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
GAT86093.1
Alpha-ketoglutarate decarboxylase.
 
 0.999
GAT86501.1
Succinate dehydrogenase.
 
 0.997
GAT86502.1
Succinate dehydrogenase; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.997
GAT86499.1
Succinate dehydrogenase.
  
 
 0.996
GAT86500.1
Succinate dehydrogenase.
  
 
 0.996
GAT88120.1
Dihydrolipoamide acetyltransferase.
 0.986
GAT88713.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.956
GAT85900.1
Type II citrate synthase; Belongs to the citrate synthase family.
  
 0.956
GAT87952.1
Isocitrate lyase.
   
 
 0.919
Your Current Organism:
Paenarthrobacter nicotinovorans
NCBI taxonomy Id: 29320
Other names: ATCC 49919, Arthrobacter nicotinivorans, Arthrobacter nicotinovorans, Arthrobacter oxydans DSM 420, CIP 106990, DSM 420, IFO 15511, JCM 3874, LMG 16253, LMG:16253, NBRC 15511, P. nicotinovorans
Server load: low (22%) [HD]