Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GAT86108.1AraC family transcriptional regulator. (322 aa)    
Predicted Functional Partners:
GAT87022.1
Phosphomethylpyrimidine kinase.
    
  0.641
sigA
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.638
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
    
  0.600
GAT88371.1
AraC family transcriptional regulator.
 
 
 0.568
GAT86107.1
Hypothetical protein.
       0.551
GAT89236.1
TenA family transcriptional regulator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family.
     
  0.534
GAT87706.1
Hypothetical protein.
    
 
 0.526
GAT87533.1
Hypothetical protein.
 
 
 0.435
GAT87077.1
Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
     
 0.421
Your Current Organism:
Paenarthrobacter nicotinovorans
NCBI taxonomy Id: 29320
Other names: ATCC 49919, Arthrobacter nicotinivorans, Arthrobacter nicotinovorans, Arthrobacter oxydans DSM 420, CIP 106990, DSM 420, IFO 15511, JCM 3874, LMG 16253, LMG:16253, NBRC 15511, P. nicotinovorans
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