| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OAH53143.1 | OAH53144.1 | AWH48_12365 | AWH48_12370 | Homocysteine methyltransferase; Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |
| OAH53143.1 | OAH55917.1 | AWH48_12365 | AWH48_04370 | Homocysteine methyltransferase; Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.892 |
| OAH53143.1 | OAH55961.1 | AWH48_12365 | AWH48_04615 | Homocysteine methyltransferase; Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.478 |
| OAH53143.1 | dnaJ | AWH48_12365 | AWH48_05165 | Homocysteine methyltransferase; Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.461 |
| OAH53143.1 | hemE | AWH48_12365 | AWH48_15035 | Homocysteine methyltransferase; Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.543 |
| OAH53143.1 | icmF | AWH48_12365 | AWH48_18895 | Homocysteine methyltransferase; Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.596 |
| OAH53144.1 | OAH53143.1 | AWH48_12370 | AWH48_12365 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homocysteine methyltransferase; Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| OAH53144.1 | OAH55917.1 | AWH48_12370 | AWH48_04370 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.923 |
| OAH53144.1 | OAH55961.1 | AWH48_12370 | AWH48_04615 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.624 |
| OAH53144.1 | hemE | AWH48_12370 | AWH48_15035 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.558 |
| OAH53144.1 | icmF | AWH48_12370 | AWH48_18895 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.537 |
| OAH55858.1 | OAH55917.1 | AWH48_04060 | AWH48_04370 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.883 |
| OAH55858.1 | OAH59667.1 | AWH48_04060 | AWH48_00750 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.992 |
| OAH55858.1 | OAH59697.1 | AWH48_04060 | AWH48_00900 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | PAS domain S-box protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.992 |
| OAH55917.1 | OAH53143.1 | AWH48_04370 | AWH48_12365 | MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homocysteine methyltransferase; Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.892 |
| OAH55917.1 | OAH53144.1 | AWH48_04370 | AWH48_12370 | MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.923 |
| OAH55917.1 | OAH55858.1 | AWH48_04370 | AWH48_04060 | MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.883 |
| OAH55917.1 | OAH55961.1 | AWH48_04370 | AWH48_04615 | MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.838 |
| OAH55917.1 | OAH59667.1 | AWH48_04370 | AWH48_00750 | MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.823 |
| OAH55917.1 | OAH59697.1 | AWH48_04370 | AWH48_00900 | MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | PAS domain S-box protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.823 |