STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureFUrease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (228 aa)    
Predicted Functional Partners:
ureG-2
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.990
ureD-2
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.990
ureE-2
Urease subunit alpha; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.987
ureC-3
Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.981
OAH54020.1
Urease accessory protein UreD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.969
OAH54021.1
Urease accessory protein UreG; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.968
ureD
Hypothetical protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.968
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.966
ureE
Urease accessory protein UreF; Too many ambiguous residues; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.947
ureE-3
Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.947
Your Current Organism:
Domibacillus aminovorans
NCBI taxonomy Id: 29332
Other names: Bacillus aminovorans, D. aminovorans, LMG 16796, LMG:16796
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