STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (296 aa)    
Predicted Functional Partners:
CCDG5_1135
Threonine synthase; High confidence in function and specificity.
 
 0.999
CCDG5_0139
Homoserine dehydrogenase; High confidence in function and specificity.
 
 0.998
CCDG5_1402
Homocysteine S-methyltransferase; High confidence in function and specificity.
    
 0.910
purM
Phosphoribosylformylglycinamidine cyclo-ligase; High confidence in function and specificity.
 
    
 0.909
lysC
Aspartokinase; High confidence in function and specificity; Belongs to the aspartokinase family.
  
 
 0.880
metC
Cystathionine beta-lyase; High confidence in function and specificity.
  
 
 0.867
ilvE
Branched-chain-amino-acid aminotransferase; High confidence in function and specificity.
  
 
 0.851
CCDG5_1555
Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
  
  0.824
cysE
Serine acetyltransferase; High confidence in function and specificity.
     
 0.823
CCDG5_2045
Hypothetical protein; High confidence in function and specificity.
    
 0.823
Your Current Organism:
Clostridium cellulosi
NCBI taxonomy Id: 29343
Other names: [. cellulosi, [Clostridium] cellulosi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.