Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
mrcAPenicillin-binding protein 1A. (879 aa)    
Predicted Functional Partners:
spoVD_1
Stage V sporulation protein D.
 
 
0.871
spoVD_3
Stage V sporulation protein D.
  
 
 0.850
spoVD_2
Stage V sporulation protein D.
  
 
0.773
dacF_3
D-alanyl-D-alanine carboxypeptidase DacF precursor; Belongs to the peptidase S11 family.
     
 0.657
vanY
D-alanyl-D-alanine carboxypeptidase.
     
  0.634
envC
Murein hydrolase activator EnvC precursor.
  
     0.630
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
   
 0.626
mepM_2
Murein DD-endopeptidase MepM.
  
   
 0.619
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
   
 0.601
ftsW
Lipid II flippase FtsW; Belongs to the SEDS family.
  
   
 0.598
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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