hemZ protein (Clostridium thermoalcaliphilum)

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Score

hemZ

Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ. (489 aa)

Predicted Functional Partners:

OPJ56775.1

0.864

hisS

0.863

dtd

0.852

relA

0.829

aspS

0.812

hemN_2

0.762

OPJ56257.1

0.717

nasF

0.657

apt

0.636

argS

0.616

Your Current Organism:

Clostridium thermoalcaliphilum

NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OPJ56257.1	hemN_2	CLOTH_06610	CLOTH_13590	Protoporphyrinogen oxidase.	Oxygen-independent coproporphyrinogen-III oxidase-like protein YqeR; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.	0.717
OPJ56257.1	hemZ	CLOTH_06610	CLOTH_00580	Protoporphyrinogen oxidase.	Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ.	0.717
OPJ56775.1	apt	CLOTH_00570	CLOTH_00540	Putative metallo-hydrolase.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.624
OPJ56775.1	aspS	CLOTH_00570	CLOTH_00600	Putative metallo-hydrolase.	aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.	0.859
OPJ56775.1	dtd	CLOTH_00570	CLOTH_00560	Putative metallo-hydrolase.	D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.	0.853
OPJ56775.1	hemZ	CLOTH_00570	CLOTH_00580	Putative metallo-hydrolase.	Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ.	0.864
OPJ56775.1	hisS	CLOTH_00570	CLOTH_00590	Putative metallo-hydrolase.	histidine--tRNA ligase.	0.880
OPJ56775.1	relA	CLOTH_00570	CLOTH_00550	Putative metallo-hydrolase.	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.894
apt	OPJ56775.1	CLOTH_00540	CLOTH_00570	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Putative metallo-hydrolase.	0.624
apt	aspS	CLOTH_00540	CLOTH_00600	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.	0.620
apt	dtd	CLOTH_00540	CLOTH_00560	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.	0.640
apt	hemZ	CLOTH_00540	CLOTH_00580	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ.	0.636
apt	hisS	CLOTH_00540	CLOTH_00590	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	histidine--tRNA ligase.	0.643
apt	relA	CLOTH_00540	CLOTH_00550	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.658
argS	aspS	CLOTH_16700	CLOTH_00600	arginine--tRNA ligase.	aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.	0.617
argS	hemZ	CLOTH_16700	CLOTH_00580	arginine--tRNA ligase.	Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ.	0.616
argS	hisS	CLOTH_16700	CLOTH_00590	arginine--tRNA ligase.	histidine--tRNA ligase.	0.615
aspS	OPJ56775.1	CLOTH_00600	CLOTH_00570	aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.	Putative metallo-hydrolase.	0.859
aspS	apt	CLOTH_00600	CLOTH_00540	aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.620
aspS	argS	CLOTH_00600	CLOTH_16700	aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.	arginine--tRNA ligase.	0.617