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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
drrADaunorubicin/doxorubicin resistance ATP-binding protein DrrA. (311 aa)    
Predicted Functional Partners:
OPJ56794.1
ABC-2 family transporter protein.
 
 
 0.973
OPJ56795.1
ABC-2 family transporter protein.
 
 
 0.966
atpD
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
    
 
 0.732
atpA
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
    
   0.715
OPJ55933.1
Putative multidrug export ATP-binding/permease protein.
 
 
0.709
OPJ55840.1
Putative ABC transporter ATP-binding protein.
 
 
0.631
OPJ55841.1
Putative ABC transporter ATP-binding protein.
 
 
0.628
atpG
ATP synthase gamma chain, sodium ion specific; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
   
   0.623
malF
Maltose transport system permease protein MalF.
     
 0.601
atpC
ATP synthase epsilon chain, sodium ion specific; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
   0.560
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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