STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsIPhosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (568 aa)    
Predicted Functional Partners:
ptsH
Phosphocarrier protein HPr.
 
 0.999
ptsG
PTS system glucose-specific EIICBA component.
 0.999
glcB
PTS system glucoside-specific EIICBA component.
 0.998
fruA_2
PTS system fructose-specific EIIBC component.
 
 
 0.997
crh
HPr-like protein Crh.
 
 0.996
malX_1
PTS system maltose- and glucose-specific EIICB component.
 
 0.929
nifJ
Pyruvate-flavodoxin oxidoreductase.
     
 0.913
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.913
sacX_1
Negative regulator of SacY activity.
  
 
 0.833
sacX_2
Negative regulator of SacY activity.
  
 
 0.833
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.