| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| birA | dapF | CLOTH_19460 | CLOTH_01810 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.460 |
| birA | nudL | CLOTH_19460 | CLOTH_01080 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Putative nudix hydrolase NudL. | 0.716 |
| birA | pncC | CLOTH_19460 | CLOTH_01150 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. | 0.504 |
| birA | pyk | CLOTH_19460 | CLOTH_18010 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.458 |
| birA | ribBA | CLOTH_19460 | CLOTH_14300 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.764 |
| birA | rph | CLOTH_19460 | CLOTH_07120 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.592 |
| cshA_1 | nudL | CLOTH_02980 | CLOTH_01080 | DEAD-box ATP-dependent RNA helicase CshA. | Putative nudix hydrolase NudL. | 0.870 |
| cshA_1 | pncC | CLOTH_02980 | CLOTH_01150 | DEAD-box ATP-dependent RNA helicase CshA. | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. | 0.412 |
| cshA_1 | rnr | CLOTH_02980 | CLOTH_08450 | DEAD-box ATP-dependent RNA helicase CshA. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.450 |
| cshA_1 | rph | CLOTH_02980 | CLOTH_07120 | DEAD-box ATP-dependent RNA helicase CshA. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.866 |
| cshA_2 | nudL | CLOTH_16330 | CLOTH_01080 | DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. | Putative nudix hydrolase NudL. | 0.870 |
| cshA_2 | pncC | CLOTH_16330 | CLOTH_01150 | DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. | 0.412 |
| cshA_2 | rnr | CLOTH_16330 | CLOTH_08450 | DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.513 |
| cshA_2 | rph | CLOTH_16330 | CLOTH_07120 | DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.866 |
| dapF | birA | CLOTH_01810 | CLOTH_19460 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.460 |
| dapF | nudL | CLOTH_01810 | CLOTH_01080 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Putative nudix hydrolase NudL. | 0.610 |
| dapF | ribBA | CLOTH_01810 | CLOTH_14300 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.731 |
| htrB | nudL | CLOTH_14780 | CLOTH_01080 | Serine protease Do-like HtrB. | Putative nudix hydrolase NudL. | 0.654 |
| nudL | birA | CLOTH_01080 | CLOTH_19460 | Putative nudix hydrolase NudL. | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.716 |
| nudL | cshA_1 | CLOTH_01080 | CLOTH_02980 | Putative nudix hydrolase NudL. | DEAD-box ATP-dependent RNA helicase CshA. | 0.870 |